{"id":"W2005905283","doi":"10.1128/jvi.76.18.9002-9010.2002","title":"The Immunogenicity and Protective Efficacy of Bovine Herpesvirus 1 Glycoprotein D plus Emulsigen Are Increased by Formulation with CpG Oligodeoxynucleotides","year":2002,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":130,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Alberta Agricultural Research Institute","keywords":"CpG Oligodeoxynucleotide; Immunogenicity; Biology; CpG site; Immune system; Antibody; Bovine herpesvirus 1; Molecular biology; Glycoprotein; Virology; Immunology; Virus; Biochemistry; Gene expression; Herpesviridae; Gene; DNA methylation","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002117543,0.000270317,0.000165634,0.0001470138,0.00006473342,0.0001577733,0.00009838842,0.000255792,0.0005030645],"category_scores_gemma":[0.000202051,0.0001081079,0.0001087627,0.00006694008,0.000172741,0.0001441796,0.00009828208,0.0002946983,0.0001030302],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000184818,"about_ca_system_score_gemma":0.0001038139,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002782267,"about_ca_topic_score_gemma":0.0003405777,"domain_scores_codex":[0.999877,0.00003138802,0.00001132887,0.0000185882,0.00002685356,0.00003489651],"domain_scores_gemma":[0.9999149,0.00002589919,0.00002144505,0.000006269512,0.00001111178,0.00002037966],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002167905,0.00003685102,0.0002163316,0.00002792101,0.000002750191,0.00001221534,0.000009197814,0.00005258095,0.9982949,0.00001627419,0.000005433126,0.001108685],"study_design_scores_gemma":[0.00004492774,0.003059782,0.003609899,0.000007830153,0.00002036802,0.0001193689,0.00001898203,0.0004035199,0.9918915,0.00002526932,0.0007954458,0.000003149697],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998624,0.0005573106,0.0004508408,0.00001575709,0.000007723889,0.000008269431,0.000027584,0.000007350147,0.0003011688],"genre_scores_gemma":[0.9986225,0.0003272303,0.0005845636,0.00002071769,0.000004168397,0.000006162496,0.00007528895,0.000002935419,0.0003563714],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005030645,"threshold_uncertainty_score":0.001682937,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01190584128470008,"score_gpt":0.2420869772736034,"score_spread":0.2301811359889033,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}