{"id":"W2005912218","doi":"10.1016/j.ijrobp.2010.03.005","title":"Ionizing Radiation Activates AMP-Activated Kinase (AMPK): A Target for Radiosensitization of Human Cancer Cells","year":2010,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":214,"is_retracted":false,"has_abstract":false,"ca_institutions":"Juravinski Cancer Centre; University of Toronto; McMaster University","funders":"","keywords":"Medicine; Ionizing radiation; AMPK; Cancer research; Radiation; Kinase; Protein kinase A; Cell biology; Irradiation; Optics; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004711503,0.000207839,0.0003915101,0.000139059,0.00009986735,0.00002717125,0.0003463336,0.0003527878,0.00007508416],"category_scores_gemma":[0.0002798729,0.0002035587,0.0002382582,0.0001271255,0.0001501003,0.00005276364,0.00004239035,0.0002821887,0.000002356255],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001380255,"about_ca_system_score_gemma":0.000406771,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002950964,"about_ca_topic_score_gemma":0.00002026524,"domain_scores_codex":[0.9984918,0.000151465,0.0006730708,0.0002659457,0.0001880849,0.0002296486],"domain_scores_gemma":[0.99706,0.0001166836,0.001426586,0.0001756276,0.001123089,0.00009800636],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002244003,0.0001638109,0.007026042,0.00001073308,0.0003249678,6.751348e-7,0.0001422308,0.0009049483,0.8496652,0.001112635,0.001507492,0.1389169],"study_design_scores_gemma":[0.002583289,0.0004065109,0.001588132,0.00001823318,0.0000676518,0.000007521678,0.00002782465,0.0003205013,0.8470499,0.002170669,0.1455754,0.0001843975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9768515,0.00468482,0.01400573,0.0002003124,0.003690993,0.0002640468,0.0002204416,0.00001339708,0.00006872219],"genre_scores_gemma":[0.985103,0.005738467,0.003745401,0.0003313622,0.004392934,0.00003236732,0.0005865481,0.00004068187,0.00002929641],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1440679,"threshold_uncertainty_score":0.8300881,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01553702759275513,"score_gpt":0.32473328797444,"score_spread":0.3091962603816848,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}