{"id":"W2005977038","doi":"10.1016/j.bbagen.2013.04.001","title":"Acceptor specificities and selective inhibition of recombinant human Gal- and GlcNAc-transferases that synthesize core structures 1, 2, 3 and 4 of O-glycans","year":2013,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - General Subjects","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"National Center for Research Resources; National Institute of General Medical Sciences; Canadian Institutes of Health Research","keywords":"Aglycone; Glycosylation; Glycan; Enzyme; Biochemistry; Chemistry; Glycosyltransferase; Transferase; Substrate (aquarium); Stereochemistry; Glycobiology; Glycoprotein; Biology; Glycoside","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000199201,0.00037865,0.0001865519,0.0001355765,0.00008683005,0.0002324467,0.0002527367,0.0002073933,0.0009158677],"category_scores_gemma":[0.0001981428,0.0001731367,0.0002159348,0.0002001087,0.000174911,0.0001430776,0.0001431444,0.0005774961,0.0002670598],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003174346,"about_ca_system_score_gemma":0.0002467788,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008960364,"about_ca_topic_score_gemma":0.0009200387,"domain_scores_codex":[0.9998399,0.00002363021,0.00001238006,0.0000236807,0.0000335151,0.00006688464],"domain_scores_gemma":[0.9998966,0.00003513885,0.00002026776,0.00001434349,0.00001113687,0.00002247561],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004446701,0.00005577375,0.0001322116,0.00001666856,0.000004918053,0.0000270198,0.0000099177,0.0001374962,0.9979359,0.0002903467,0.00003746573,0.000907666],"study_design_scores_gemma":[0.0000139639,0.0001322861,0.0006286586,0.000001174417,0.000008029237,0.00008070534,0.00000387256,0.0004447288,0.9981543,0.00003423787,0.0004967363,0.000001381844],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939939,0.0008343612,0.002996414,0.00004921142,0.00002935778,0.00001702353,0.0002978532,0.0000405934,0.001741246],"genre_scores_gemma":[0.9944932,0.0007816693,0.001505128,0.00003521521,0.00001347003,0.00002141569,0.0008282974,0.00002657608,0.002294949],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009158677,"threshold_uncertainty_score":0.003063858,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02277406180973564,"score_gpt":0.266922976016668,"score_spread":0.2441489142069324,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}