{"id":"W2005981959","doi":"10.1038/cdd.2009.161","title":"Granzymes and perforin in solid organ transplant rejection","year":2009,"lang":"en","type":"review","venue":"Cell Death and Differentiation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":107,"is_retracted":false,"has_abstract":false,"ca_institutions":"Simon Fraser University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Perforin; Granzyme; Effector; Solid organ; Cytotoxic T cell; Immunology; Granulysin; Organ transplantation; Immune system; Biology; Granzyme A; Transplantation; Medicine; CD8","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001001216,0.000292498,0.0006586649,0.0003093508,0.0001373166,0.00003981096,0.00005050585,0.000472659,0.0002156174],"category_scores_gemma":[0.0000096528,0.0002396014,0.0001066909,0.00009439066,0.00002552217,0.0001116383,0.00001523024,0.0004232333,0.0000699802],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005126475,"about_ca_system_score_gemma":0.00002600669,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004302966,"about_ca_topic_score_gemma":0.00001561185,"domain_scores_codex":[0.9988077,0.0001872548,0.000417351,0.0003505215,0.00002554444,0.0002116299],"domain_scores_gemma":[0.9995922,0.0000582338,0.000181196,0.0001247038,0.00002164005,0.00002202158],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008307334,0.0001713661,0.0003815631,0.002621528,0.00007199701,0.000002818206,0.0003240266,1.882323e-7,0.001704626,0.0001623617,0.0003677109,0.9941087],"study_design_scores_gemma":[0.001425973,0.0003196905,0.003903061,0.002934585,0.0007070966,0.000190595,0.00006437526,0.00001999218,0.001414358,0.00006485159,0.9884287,0.0005267641],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006033092,0.9912434,0.0001376175,0.000008286872,0.001284262,0.0003553182,0.000005975839,0.00004243399,0.0008896245],"genre_scores_gemma":[0.03577176,0.9583867,0.000004237317,0.00001949844,0.00003839453,0.0000227145,0.001090545,0.00001771504,0.0046484],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.993582,"threshold_uncertainty_score":0.9770661,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01878864899302021,"score_gpt":0.2551717018638485,"score_spread":0.2363830528708283,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}