{"id":"W2006068238","doi":"10.1016/j.ccr.2008.10.013","title":"Glycogen Synthase Kinase-3 and Cancer: Good Cop, Bad Cop?","year":2008,"lang":"en","type":"article","venue":"Cancer Cell","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":97,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute","funders":"Canadian Institutes of Health Research","keywords":"GSK-3; Glycogen synthase; ATP synthase; GSK3B; Chemistry; Glycogen; Kinase; Biology; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006778519,0.0002147345,0.0001852231,0.00002049416,0.0001714798,0.00001690775,0.0001852899,0.0001542113,0.0005892129],"category_scores_gemma":[0.000007877219,0.0002097502,0.00006320425,0.00008097082,0.0001465794,0.000006489764,0.00009925901,0.00008620953,0.00001752229],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006827868,"about_ca_system_score_gemma":0.0003280377,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004797089,"about_ca_topic_score_gemma":0.000158043,"domain_scores_codex":[0.9988708,0.00002601656,0.0001839958,0.0004468223,0.0001441664,0.0003281624],"domain_scores_gemma":[0.9994318,0.000009723049,0.0000811512,0.0002425171,0.00008691703,0.0001478809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000204387,0.00007462719,0.03310641,0.00008452252,0.0001269312,0.00003860658,0.0002873338,0.00009883993,0.8763967,0.00001631777,0.08091973,0.008645593],"study_design_scores_gemma":[0.0008254376,0.00007968689,0.001505862,0.00002997796,0.00003408513,0.00001214963,0.00003771059,0.0000164984,0.6505298,0.000009088679,0.3466067,0.0003130362],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9278846,0.06465084,0.00008286355,0.0001579158,0.0005072857,0.0001822032,0.0000872092,0.0000259875,0.006421078],"genre_scores_gemma":[0.9585768,0.0303229,0.000264598,0.0006784613,0.000512616,0.0001740626,0.0000687184,0.00003967354,0.009362151],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.265687,"threshold_uncertainty_score":0.8553364,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01259428163719027,"score_gpt":0.2397654394102144,"score_spread":0.2271711577730242,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}