{"id":"W2006070115","doi":"10.1016/j.ccr.2012.03.041","title":"Lunatic Fringe Deficiency Cooperates with the Met/Caveolin Gene Amplicon to Induce Basal-like Breast Cancer","year":2012,"lang":"en","type":"article","venue":"Cancer Cell","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":133,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute for Clinical Evaluative Sciences; SickKids Foundation; University of Toronto; University Health Network; Princess Margaret Cancer Centre; Hospital for Sick Children","funders":"National Cancer Institute; Sociedad Española de Oncología Médica; Hospital for Sick Children; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Genome Canada; Breast Cancer Research Foundation; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Susan G. Komen for the Cure","keywords":"Notch signaling pathway; Biology; Progenitor cell; Cancer research; Cell biology; Stem cell; Caveolin 1; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001688605,0.0003284217,0.000257879,0.0005001142,0.000343018,0.000424913,0.0003347755,0.0004847774,0.002785996],"category_scores_gemma":[0.0001797191,0.0002914401,0.0003572454,0.0002357114,0.0004377229,0.0001669704,0.0003474491,0.0008306326,0.0008068898],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005900813,"about_ca_system_score_gemma":0.0003455339,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002117529,"about_ca_topic_score_gemma":0.003691273,"domain_scores_codex":[0.9997891,0.00003573067,0.00001982212,0.00003084132,0.00005463969,0.00006995938],"domain_scores_gemma":[0.9997601,0.00005649053,0.00004800429,0.00004189181,0.000009491013,0.00008390496],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001650575,0.00003088605,0.0001270568,0.00001428151,0.000006532504,0.0001611774,0.000006674789,0.00005183008,0.9987844,0.0001468605,0.00007534683,0.0004300048],"study_design_scores_gemma":[0.00004047683,0.0001169824,0.00303973,0.000002333211,0.00001484658,0.0007530557,0.00003103653,0.0009863483,0.9927202,0.00006204213,0.002226593,0.00000641568],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934183,0.0006890672,0.002583337,0.0002486535,0.00005735246,0.00003631823,0.0007601762,0.0002652576,0.001941599],"genre_scores_gemma":[0.9944945,0.0001715843,0.001011256,0.00005062966,0.000005235948,0.00002226124,0.0004639255,0.00004479956,0.003735792],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002785996,"threshold_uncertainty_score":0.00932014,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02167324075619788,"score_gpt":0.278975598176906,"score_spread":0.2573023574207081,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}