{"id":"W2006070115","doi":"10.1016/j.ccr.2012.03.041","title":"Lunatic Fringe Deficiency Cooperates with the Met/Caveolin Gene Amplicon to Induce Basal-like Breast Cancer","year":2012,"lang":"en","type":"article","venue":"Cancer Cell","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":133,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute for Clinical Evaluative Sciences; SickKids Foundation; University of Toronto; University Health Network; Princess Margaret Cancer Centre; Hospital for Sick Children","funders":"National Cancer Institute; Sociedad Española de Oncología Médica; Hospital for Sick Children; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Genome Canada; Breast Cancer Research Foundation; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Susan G. Komen for the Cure","keywords":"Notch signaling pathway; Biology; Progenitor cell; Cancer research; Cell biology; Stem cell; Caveolin 1; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002489428,0.0003044684,0.0003969719,0.00006543961,0.0001658473,0.00004259598,0.0002101464,0.00006995606,0.001921118],"category_scores_gemma":[0.000006348062,0.0001843459,0.00008624169,0.0005326971,0.00009141591,0.0001465604,0.000079808,0.0002466032,0.00009251458],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004549988,"about_ca_system_score_gemma":0.0004199655,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005479529,"about_ca_topic_score_gemma":0.001218402,"domain_scores_codex":[0.9982268,0.00004307295,0.0002358355,0.0003999119,0.0003748879,0.0007194489],"domain_scores_gemma":[0.9986512,0.00004817811,0.0001032897,0.0005232678,0.0002201892,0.000453861],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001911305,0.001664086,0.132256,0.001416135,0.0006881963,0.00005598786,0.01472236,0.001816412,0.6197445,0.0004297507,0.1050714,0.1202238],"study_design_scores_gemma":[0.004887261,0.0006451422,0.09675885,0.0005115145,0.001882176,0.0001629551,0.002392674,0.00008862104,0.5112641,0.000008366183,0.3800463,0.001351963],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9597998,0.02894073,0.0003241462,0.003100402,0.0008678368,0.0008963582,0.000186271,0.00006166272,0.005822832],"genre_scores_gemma":[0.9853027,0.00168141,0.0004898479,0.007022099,0.0008665459,0.0004795672,0.00001080545,0.00007249705,0.004074467],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2749749,"threshold_uncertainty_score":0.9989913,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02167324075619788,"score_gpt":0.278975598176906,"score_spread":0.2573023574207081,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}