{"id":"W2006137883","doi":"10.1038/nrmicro3240","title":"Semi-synthetic artemisinin: a model for the use of synthetic biology in pharmaceutical development","year":2014,"lang":"en","type":"review","venue":"Nature Reviews Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":674,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Research Council Canada; Sanofi","keywords":"Synthetic biology; Artemisinin; Metabolic engineering; Biology; Biochemical engineering; Drug discovery; Biotechnology; Systems biology; Computational biology; Malaria; Bioinformatics; Plasmodium falciparum; Engineering; Biochemistry; Immunology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07851563570554373,"score_gpt":0.4105401902620697,"score_spread":0.332024554556526,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}