{"id":"W2006163287","doi":"10.1242/dev.056291","title":"RACK1 is a novel interaction partner of PTK7 that is required for neural tube closure","year":2011,"lang":"en","type":"article","venue":"Development","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":100,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Deutsche Forschungsgemeinschaft","keywords":"Biology; Neural tube; Dishevelled; Cell biology; Convergent extension; Xenopus; Cell polarity; Cell adhesion; Neural plate; Signal transducing adaptor protein; Wnt signaling pathway; Signal transduction; Cell; Frizzled; Embryo; Genetics; Embryogenesis; Gastrulation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001154088,0.000493624,0.0002850634,0.0004028576,0.0006036668,0.000391136,0.0003716456,0.000428537,0.001965692],"category_scores_gemma":[0.0001357069,0.0002644977,0.0003517602,0.0001342803,0.0002490107,0.000293712,0.0003393485,0.0007373189,0.001219239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006336856,"about_ca_system_score_gemma":0.00034089,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005140518,"about_ca_topic_score_gemma":0.0008402426,"domain_scores_codex":[0.9997951,0.00002115616,0.00001981087,0.00005246507,0.00007739813,0.00003416789],"domain_scores_gemma":[0.999855,0.00001372456,0.00003793183,0.00001656348,0.00001820496,0.00005854822],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004817971,0.00001151168,0.0002854906,0.00002311256,0.000004947205,0.0002485055,0.000007322365,0.00005725997,0.9979825,0.0001874364,0.00009775192,0.001045919],"study_design_scores_gemma":[0.00001550039,0.0000554976,0.01028927,0.000005972593,0.0000210358,0.00218956,0.00002750271,0.001735846,0.9783945,0.0001095178,0.007144613,0.00001119157],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9848862,0.003132358,0.006652414,0.0003310612,0.0001031543,0.00003200861,0.0009016615,0.0004121506,0.00354892],"genre_scores_gemma":[0.9902405,0.0005698477,0.002736436,0.00006330597,0.00001334964,0.00002796544,0.001749647,0.0000947237,0.004504319],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001965692,"threshold_uncertainty_score":0.006575942,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07683501415838474,"score_gpt":0.2884098540763614,"score_spread":0.2115748399179767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}