{"id":"W2006163287","doi":"10.1242/dev.056291","title":"RACK1 is a novel interaction partner of PTK7 that is required for neural tube closure","year":2011,"lang":"en","type":"article","venue":"Development","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":100,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Deutsche Forschungsgemeinschaft","keywords":"Biology; Neural tube; Dishevelled; Cell biology; Convergent extension; Xenopus; Cell polarity; Cell adhesion; Neural plate; Signal transducing adaptor protein; Wnt signaling pathway; Signal transduction; Cell; Frizzled; Embryo; Genetics; Embryogenesis; Gastrulation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009903566,0.0001210191,0.0001126055,0.00004037635,0.00005820564,0.00001028593,0.0001080336,0.00009418539,0.0001691939],"category_scores_gemma":[0.0000141685,0.0001141589,0.0001049448,0.00003974216,0.00001408753,0.000006491624,0.00007348559,0.00004920971,0.00001020488],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001674331,"about_ca_system_score_gemma":0.00006236463,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001291771,"about_ca_topic_score_gemma":0.00001824016,"domain_scores_codex":[0.9992658,0.000009006915,0.0002259386,0.0002491522,0.00009064755,0.0001594053],"domain_scores_gemma":[0.9995031,0.000004431583,0.0001138068,0.0002099718,0.0001216373,0.00004704801],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002496824,0.0002292702,0.0008484254,0.00003404012,0.0002182228,5.732175e-7,0.001632557,0.00000142446,0.9755741,0.000245165,0.01445719,0.0065093],"study_design_scores_gemma":[0.0003146644,0.0001095775,0.0008840482,0.00001231884,0.00001416779,0.00000707675,0.0001247087,0.0001412509,0.7047734,0.0000236661,0.2934862,0.0001089264],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9725224,0.0001336484,0.02467036,0.0002064273,0.0007128243,0.0003193156,0.00004020068,0.000008965868,0.001385824],"genre_scores_gemma":[0.9902614,0.00003354792,0.006476872,0.0005879276,0.0000693758,0.00006687097,0.0001635203,0.00001988818,0.002320638],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.279029,"threshold_uncertainty_score":0.4655264,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07683501415838474,"score_gpt":0.2884098540763614,"score_spread":0.2115748399179767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}