{"id":"W2006176570","doi":"10.1038/cmi.2008.51","title":"Acquired pMHC I Complexes Greatly Enhance CD4+ Th Cell's Stimulatory Effect on CD8+ T Cell-Mediated Diabetes in Transgenic RIP-mOVA Mice","year":2008,"lang":"en","type":"article","venue":"Cellular and Molecular Immunology","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan; Saskatchewan Cancer Agency","funders":"","keywords":"Transgene; Genetically modified mouse; Diabetes mellitus; CD8; Cell biology; Cell; Cytotoxic T cell; Biology; T cell; Immunology; Cancer research; Endocrinology; Immune system; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002865034,0.0008307794,0.0005186756,0.0007260252,0.0002794306,0.0005209802,0.0005044403,0.0007005468,0.003399117],"category_scores_gemma":[0.0002229459,0.0004130936,0.0004065138,0.0002343791,0.0004361683,0.0004302084,0.0004111814,0.002268703,0.001043542],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00041804,"about_ca_system_score_gemma":0.0002630228,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004838827,"about_ca_topic_score_gemma":0.0006723159,"domain_scores_codex":[0.9994794,0.0000875492,0.00005208215,0.0001014121,0.00008538927,0.0001941577],"domain_scores_gemma":[0.9993736,0.0001017437,0.0001585499,0.00006801992,0.00003549558,0.0002626335],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001570499,0.00004204575,0.00006404661,0.0000166166,0.000003290434,0.00003960247,0.000007806694,0.00002633348,0.9992923,0.00007702043,0.0000333561,0.0002406011],"study_design_scores_gemma":[0.0000517573,0.0002061479,0.001670496,0.000006095967,0.00002105863,0.0001961048,0.0000169949,0.0004584104,0.9963845,0.00004551494,0.0009385559,0.000004357896],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924838,0.0009171084,0.002713636,0.0002568908,0.00009530904,0.00003738569,0.0005759169,0.0003428502,0.002576943],"genre_scores_gemma":[0.9907315,0.0004523665,0.003236781,0.0001439871,0.00008198379,0.00006625972,0.0007337932,0.0002251957,0.00432816],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003399117,"threshold_uncertainty_score":0.01137114,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003943521713429416,"score_gpt":0.198232611514087,"score_spread":0.1942890898006576,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}