{"id":"W2006179410","doi":"10.1002/cncr.25413","title":"Treatment of pituitary neoplasms with temozolomide","year":2010,"lang":"en","type":"review","venue":"Cancer","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":106,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"","keywords":"Temozolomide; Medicine; Methyltransferase; Pituitary adenoma; Pituitary tumors; O-6-methylguanine-DNA methyltransferase; Internal medicine; Oncology; Cancer; Chemotherapy; Pituitary neoplasm; Cancer research; Pathology; Adenoma; Pituitary gland; DNA; Methylation; Hormone; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001542723,0.0001887123,0.0003056944,0.0004147512,0.0001248683,0.0001427242,0.000148386,0.0001019638,0.0006252695],"category_scores_gemma":[0.000299252,0.00006234106,0.0003032248,0.0004153782,0.0001269217,0.0001686302,0.0001469719,0.0002034068,0.0001302278],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002730859,"about_ca_system_score_gemma":0.0003450061,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009658226,"about_ca_topic_score_gemma":0.002620719,"domain_scores_codex":[0.9999355,0.00001457474,0.00001323267,0.00001032962,0.0000180425,0.000008343134],"domain_scores_gemma":[0.9999086,0.00002979792,0.00003450052,0.000004778268,0.00001325951,0.000009193662],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003494609,0.0002383107,0.01929365,0.02138724,0.0008853396,0.01158917,0.0004285569,0.0005913742,0.3116679,0.0007064317,0.004692149,0.6250253],"study_design_scores_gemma":[0.001465656,0.006671785,0.2805221,0.002862165,0.003263137,0.08193669,0.0009327602,0.001550433,0.3230121,0.001187246,0.296495,0.0001008401],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.3451621,0.6451961,0.002747563,0.0004864472,0.000126605,0.00009324322,0.0004783986,0.00009687174,0.005612651],"genre_scores_gemma":[0.6960084,0.2983011,0.002996665,0.0003659225,0.000138629,0.00005947196,0.0007566169,0.00001361431,0.001359652],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0009658226,"threshold_uncertainty_score":0.002091765,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04572498512695851,"score_gpt":0.3577204973659142,"score_spread":0.3119955122389557,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}