{"id":"W2006195669","doi":"10.1016/j.micron.2009.05.005","title":"Interaction of doxorubicin with the subcellular structures of the sensitive and Bcl-xL-overexpressing MCF-7 cell line: Confocal and low-energy-loss transmission electron microscopy","year":2009,"lang":"en","type":"article","venue":"Micron","topic":"Electron Spin Resonance Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Confocal; Cytoplasm; Nucleolus; Confocal microscopy; Intracellular; Biophysics; Doxorubicin; Cell culture; Electron microscope; Cell biology; Biology; Mitochondrion; Optics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000602357,0.0001405282,0.0001521365,0.00001583892,0.00009572733,0.00001150426,0.00007454977,0.00008013003,7.695413e-7],"category_scores_gemma":[0.000004019665,0.00007965491,0.00003801104,0.00004920201,0.0002250379,0.000004396771,0.00003383767,0.0001131352,2.816081e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009262513,"about_ca_system_score_gemma":0.00003131342,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000461846,"about_ca_topic_score_gemma":0.00002931882,"domain_scores_codex":[0.9993543,0.00006340658,0.0001325042,0.0002089664,0.00007970404,0.0001611055],"domain_scores_gemma":[0.9996247,0.00001386334,0.0001281169,0.0001529331,0.00006108008,0.00001931426],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004005989,0.00002201689,0.0001667409,0.00002764061,0.00002222757,6.437792e-7,0.0002210315,0.00002125864,0.9964992,0.00002584768,0.0001495792,0.00244317],"study_design_scores_gemma":[0.0004988594,0.0005562805,0.004037236,0.00006749171,0.00003167053,0.00002003019,0.0001412944,0.00002949436,0.9927632,0.00002994566,0.001731526,0.00009294699],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916756,0.006668713,0.001142431,0.0002923177,0.00001522742,0.0001117586,0.000006786852,0.000002609271,0.00008454326],"genre_scores_gemma":[0.9986664,0.0008323807,0.000188265,0.0001400691,0.00003717888,0.000001317907,0.000008056772,0.000009851943,0.000116448],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006990819,"threshold_uncertainty_score":0.3248233,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002351890831224578,"score_gpt":0.2238686566093889,"score_spread":0.2215167657781643,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}