{"id":"W2006195669","doi":"10.1016/j.micron.2009.05.005","title":"Interaction of doxorubicin with the subcellular structures of the sensitive and Bcl-xL-overexpressing MCF-7 cell line: Confocal and low-energy-loss transmission electron microscopy","year":2009,"lang":"en","type":"article","venue":"Micron","topic":"Electron Spin Resonance Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Confocal; Cytoplasm; Nucleolus; Confocal microscopy; Intracellular; Biophysics; Doxorubicin; Cell culture; Electron microscope; Cell biology; Biology; Mitochondrion; Optics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000299266,0.0001886278,0.0002929737,0.0002508398,0.0004450757,0.0003266042,0.0003775774,0.0003873286,0.00165449],"category_scores_gemma":[0.0001687004,0.0002308181,0.0002565577,0.000222351,0.0003044275,0.0003965741,0.0001921584,0.0006889002,0.0004189179],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007642171,"about_ca_system_score_gemma":0.0002762659,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004896278,"about_ca_topic_score_gemma":0.005345033,"domain_scores_codex":[0.9998432,0.00002683455,0.00001034104,0.00002556033,0.0000475445,0.0000464395],"domain_scores_gemma":[0.9998097,0.00008658425,0.00002053963,0.000030426,0.00003209666,0.00002071089],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000122791,0.00002487366,0.0001728825,0.00003301507,0.000007092347,0.00006356475,0.00006042044,0.00006894962,0.9985179,0.0003592688,0.00005738025,0.0005117149],"study_design_scores_gemma":[0.00001628162,0.0001110186,0.008664852,0.000007719682,0.00001595688,0.0003664566,0.0001250035,0.00197055,0.9871278,0.00007982492,0.001504535,0.000009933618],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989342,0.001536489,0.005297252,0.0002350768,0.00003474148,0.00002349982,0.0004105812,0.00005818021,0.003061997],"genre_scores_gemma":[0.9870254,0.001226889,0.006951505,0.000100927,0.00001381383,0.00004513013,0.0005217448,0.00003929449,0.004075395],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004896278,"threshold_uncertainty_score":0.009735584,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002351890831224578,"score_gpt":0.2238686566093889,"score_spread":0.2215167657781643,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}