{"id":"W2006236789","doi":"10.1038/sj.onc.1209520","title":"SLP65 deficiency results in perpetual V(D)J recombinase activity in pre-B-lymphoblastic leukemia and B-cell lymphoma cells","year":2006,"lang":"en","type":"article","venue":"Oncogene","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Deutsche Forschungsgemeinschaft; Stem Cell Network","keywords":"Biology; Recombinase; Leukemia; Cancer research; Lymphoma; BCL10; Gene rearrangement; Chronic lymphocytic leukemia; RAG2; B cell; Recombination-activating gene; Lymphoid leukemia; Molecular biology; Gene; Immunology; Genetics; Antibody","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000254436,0.0003963826,0.0002729677,0.0006551719,0.0002731732,0.0008441734,0.0003546302,0.0004233128,0.002002985],"category_scores_gemma":[0.0001890853,0.00036997,0.0003068706,0.0004088898,0.0004002686,0.0003108102,0.0004081429,0.0008212411,0.0009240478],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004591584,"about_ca_system_score_gemma":0.0003643194,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001294232,"about_ca_topic_score_gemma":0.001410235,"domain_scores_codex":[0.9996592,0.00004856816,0.00006778677,0.0000537881,0.0000786137,0.00009199029],"domain_scores_gemma":[0.9995959,0.00007992412,0.00009184107,0.00006236493,0.00001784864,0.000152024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002144446,0.00005269223,0.000713931,0.00001998274,0.000009284026,0.0003575575,0.00002715109,0.00008478307,0.9973763,0.0005266613,0.00004675196,0.0005703981],"study_design_scores_gemma":[0.00005562256,0.0001936372,0.008812523,0.000006849692,0.00003927887,0.001905732,0.0001332736,0.000839033,0.9856418,0.000189324,0.002175845,0.000007136709],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961123,0.0007692071,0.001441399,0.00005206604,0.00001686083,0.00001785546,0.0004590124,0.0001309278,0.001000443],"genre_scores_gemma":[0.9969292,0.0002440133,0.0004922301,0.00002140961,0.000004397399,0.00001612887,0.0004737978,0.00003021615,0.001788533],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002002985,"threshold_uncertainty_score":0.006700635,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005237563773556121,"score_gpt":0.2110131457590791,"score_spread":0.205775581985523,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}