{"id":"W2006255713","doi":"10.1097/00002030-200003100-00012","title":"Phase III study of granulocyte-macrophage colony-stimulating factor in advanced HIV disease: effect on infections, CD4 cell counts and HIV suppression","year":2000,"lang":"en","type":"article","venue":"AIDS","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Research & Development Corporation; AIDS Committee of Toronto; Ottawa Hospital; University of Ottawa","funders":"","keywords":"Medicine; Placebo; Granulocyte macrophage colony-stimulating factor; Internal medicine; Immunology; Granulocyte colony-stimulating factor; Lentivirus; Risk factor; Incidence (geometry); Immunopathology; Gastroenterology; Viral disease; Cytokine; Human immunodeficiency virus (HIV); Chemotherapy; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00007240594,0.0001063434,0.0001877601,0.00007898173,0.0000946635,0.000005052537,0.00004716092,0.00005394724,0.001254828],"category_scores_gemma":[0.00002949268,0.00008201344,0.00002661886,0.00008542059,0.00004625458,0.00004083209,0.00002110513,0.0001410957,0.0003825351],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002962039,"about_ca_system_score_gemma":0.0000173042,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003395865,"about_ca_topic_score_gemma":0.000005301485,"domain_scores_codex":[0.9992412,0.0002161851,0.0001375381,0.0001859854,0.00004039206,0.0001786676],"domain_scores_gemma":[0.9995718,0.0002033911,0.00002844327,0.0001489274,0.00001258195,0.00003486521],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005693567,0.009269645,0.7415153,0.000087236,0.0001465858,0.0001316922,0.000903608,0.0001849721,0.1279657,0.000006030496,0.0009970992,0.1130986],"study_design_scores_gemma":[0.177617,0.05084391,0.5809101,0.0003840178,0.0002372238,0.00001263056,0.0003796044,0.0001856878,0.1711142,0.00003117773,0.01753353,0.0007509664],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977438,0.0006609662,0.000002993449,0.000004965631,0.00005485186,0.0005568169,0.000161097,0.00001952222,0.0007949312],"genre_scores_gemma":[0.9975716,0.00004913446,0.000005107501,0.000006096436,0.000004877673,0.00005137879,0.000136899,0.00000784945,0.002167004],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1719234,"threshold_uncertainty_score":0.9996582,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007703030385645415,"score_gpt":0.2941739656881886,"score_spread":0.2864709353025432,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}