{"id":"W2006274666","doi":"10.1006/mthe.2002.0573","title":"Unfulfilled Promise of Endostatin in a Gene Therapy-Xenotransplant Model of Human Acute Lymphocytic Leukemia","year":2002,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Heart, Lung, and Blood Institute","keywords":"Genetic enhancement; Leukemia; Medicine; Cancer research; Immunology; Gene; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004455523,0.0005962399,0.0003745393,0.0006069862,0.0002928095,0.0005820478,0.0004510042,0.0007043278,0.001452445],"category_scores_gemma":[0.0001144604,0.0001840999,0.0003510279,0.0002827734,0.000628247,0.0007290707,0.0003018303,0.001164127,0.0003841413],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004481727,"about_ca_system_score_gemma":0.0004324676,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006679011,"about_ca_topic_score_gemma":0.0007183737,"domain_scores_codex":[0.9997181,0.0000576358,0.00002778638,0.00005803131,0.00008501943,0.00005347839],"domain_scores_gemma":[0.9998814,0.00001697153,0.00003003923,0.00002272732,0.000007754145,0.00004106209],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009913055,0.0007124944,0.0001254794,0.0000756093,0.00001000077,0.0002094602,0.00005832913,0.0003319805,0.9931646,0.001447624,0.0001414574,0.002731721],"study_design_scores_gemma":[0.0002263985,0.005270477,0.0008310192,0.00001876509,0.0000431904,0.0006008653,0.0000612685,0.002298636,0.9833951,0.0003955409,0.006846739,0.00001202542],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9837713,0.002642856,0.008869858,0.0006380852,0.0002625742,0.0002297314,0.0006862772,0.0003216231,0.002577756],"genre_scores_gemma":[0.9852893,0.001904811,0.006312779,0.0001181024,0.00004909881,0.0002551325,0.0005212624,0.00004450025,0.005505004],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001452445,"threshold_uncertainty_score":0.004858911,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02480497774315387,"score_gpt":0.2572907532101729,"score_spread":0.232485775467019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}