{"id":"W2006274666","doi":"10.1006/mthe.2002.0573","title":"Unfulfilled Promise of Endostatin in a Gene Therapy-Xenotransplant Model of Human Acute Lymphocytic Leukemia","year":2002,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Heart, Lung, and Blood Institute","keywords":"Genetic enhancement; Leukemia; Medicine; Cancer research; Immunology; Gene; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001109552,0.0002194176,0.0003212879,0.00008116679,0.00003030445,0.000005904101,0.0002628568,0.0001558416,0.00006768842],"category_scores_gemma":[0.000003657364,0.0001953107,0.0002228459,0.0001343671,0.00009604789,0.000003448007,0.00002495094,0.00005222865,0.000001796144],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000742935,"about_ca_system_score_gemma":0.0001163477,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008010317,"about_ca_topic_score_gemma":0.000008284889,"domain_scores_codex":[0.9987572,0.00007207909,0.0003941692,0.0003344031,0.0001877771,0.0002544073],"domain_scores_gemma":[0.9992731,0.000005976052,0.0001549354,0.0004399751,0.00007347887,0.00005259294],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003332762,0.0001083815,0.0002583053,0.00001552499,0.0002060382,0.00001409691,0.0003167608,0.00462858,0.9910361,0.00006398321,0.00005486794,0.002964115],"study_design_scores_gemma":[0.004054282,0.0004887519,0.0001319136,0.00002301614,0.0000166865,0.000006796831,0.00001288356,0.005028336,0.9896947,0.00009769533,0.0002394014,0.0002055901],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989114,0.008252169,0.001807083,0.00002003747,0.00002296236,0.0003589308,0.00005961319,0.000007896233,0.0003573035],"genre_scores_gemma":[0.9898968,0.008429943,0.0009934619,0.0002570306,0.000021384,0.000066447,0.00005959134,0.00004602125,0.0002292803],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003721006,"threshold_uncertainty_score":0.7964538,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02480497774315387,"score_gpt":0.2572907532101729,"score_spread":0.232485775467019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}