{"id":"W2006309936","doi":"10.1126/science.1098419","title":"The Radical Site in Chlamydial Ribonucleotide Reductase Defines a New R2 Subclass","year":2004,"lang":"en","type":"article","venue":"Science","topic":"Metal-Catalyzed Oxygenation Mechanisms","field":"Chemistry","cited_by":156,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Health Canada","funders":"","keywords":"Ribonucleotide reductase; Deoxyribonucleotides; Chemistry; Ribonucleotide; Active site; Stereochemistry; Ligand (biochemistry); Biochemistry; Enzyme; Nucleotide; Receptor; Protein subunit; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001745949,0.0003592306,0.0002888473,0.000450748,0.0004599243,0.0007273313,0.0004622327,0.0003823413,0.000971386],"category_scores_gemma":[0.0001989345,0.0001671396,0.0002806104,0.0002862446,0.0003672332,0.0003631645,0.0004677829,0.0005003466,0.0006688397],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007163696,"about_ca_system_score_gemma":0.0004482786,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00450258,"about_ca_topic_score_gemma":0.003118959,"domain_scores_codex":[0.9997897,0.00001078268,0.000009340919,0.00008540494,0.00004434483,0.00006056014],"domain_scores_gemma":[0.9997919,0.00001616074,0.00004107914,0.00003394102,0.00003544199,0.00008142167],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002926867,0.00007330292,0.008926543,0.00007445869,0.00001465881,0.0002056792,0.0002675419,0.0001006761,0.9708283,0.002474992,0.0003829424,0.01635816],"study_design_scores_gemma":[0.0001145951,0.001521954,0.2895404,0.0001436732,0.000155865,0.00961018,0.001156195,0.003065481,0.4978288,0.004112167,0.1926231,0.0001276751],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.984246,0.003335221,0.005515093,0.0001309968,0.00003517401,0.00002849567,0.000375404,0.0002014086,0.006132145],"genre_scores_gemma":[0.9851227,0.001230578,0.005878451,0.0001873725,0.00003575722,0.00002718795,0.00131873,0.0000603587,0.006138779],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00450258,"threshold_uncertainty_score":0.008952796,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01304837282999138,"score_gpt":0.2503665539636509,"score_spread":0.2373181811336595,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}