{"id":"W2006328525","doi":"10.1099/mic.0.29121-0","title":"Genetic tools for highly pathogenic Francisella tularensis subsp. tularensis","year":2006,"lang":"en","type":"article","venue":"Microbiology","topic":"Bacillus and Francisella bacterial research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Institutes of Health; University of Victoria","keywords":"Francisella tularensis; Biology; Kanamycin; Plasmid; Genetics; Tularemia; Amp resistance; Microbiology; Attenuated vaccine; Shuttle vector; Selectable marker; Gene; Virology; Vector (molecular biology); Virulence; Recombinant DNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002377339,0.0003004001,0.0003618933,0.00008036365,0.000171653,0.00006823891,0.0003453392,0.0004842017,0.0001026135],"category_scores_gemma":[0.0001254263,0.0002846758,0.000299086,0.0001323507,0.0002005868,0.000004807096,0.0001439494,0.0001109215,0.00009027396],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002757855,"about_ca_system_score_gemma":0.0001050482,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008904998,"about_ca_topic_score_gemma":0.0002421055,"domain_scores_codex":[0.9979206,0.0001152371,0.0004121795,0.0007320418,0.0000638768,0.0007560765],"domain_scores_gemma":[0.9988951,0.00006296825,0.0001001276,0.0005692334,0.0002753602,0.00009720974],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002114292,0.00006420601,0.0008545172,0.00002703848,0.0000556397,0.000007757896,0.000007108539,0.00001979692,0.9835889,0.00009597886,0.008707971,0.006359691],"study_design_scores_gemma":[0.001151594,0.0003925813,0.005508941,0.000006169334,0.00003414208,0.00008405343,0.000006634516,0.00001336815,0.709323,0.0002249411,0.2828749,0.0003796395],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9870024,0.003104882,0.00759325,0.0001632752,0.0005132786,0.0005631621,0.0006350308,0.00003090627,0.0003937612],"genre_scores_gemma":[0.9911926,0.0001656749,0.004660157,0.0003560897,0.0009616024,0.0001085072,0.001767225,0.00006503633,0.0007230975],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2742658,"threshold_uncertainty_score":0.9999605,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01029627031217081,"score_gpt":0.2255703693197669,"score_spread":0.2152740990075961,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}