{"id":"W2006328525","doi":"10.1099/mic.0.29121-0","title":"Genetic tools for highly pathogenic Francisella tularensis subsp. tularensis","year":2006,"lang":"en","type":"article","venue":"Microbiology","topic":"Bacillus and Francisella bacterial research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Institutes of Health; University of Victoria","keywords":"Francisella tularensis; Biology; Kanamycin; Plasmid; Genetics; Tularemia; Amp resistance; Microbiology; Attenuated vaccine; Shuttle vector; Selectable marker; Gene; Virology; Vector (molecular biology); Virulence; Recombinant DNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006454988,0.0008004676,0.0005949872,0.002132272,0.0008220933,0.0006992982,0.000984106,0.0009758798,0.001631517],"category_scores_gemma":[0.000877383,0.000531799,0.0007127744,0.000789709,0.0003845013,0.0006277398,0.001385452,0.00133726,0.002120139],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005879984,"about_ca_system_score_gemma":0.0007239535,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001267975,"about_ca_topic_score_gemma":0.002741244,"domain_scores_codex":[0.9992871,0.000104987,0.0001086615,0.0000660305,0.0003278617,0.0001054429],"domain_scores_gemma":[0.9994243,0.0001520695,0.0001632738,0.0000994759,0.00008479624,0.00007607279],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004006011,0.00006767074,0.000213846,0.000170475,0.00001120728,0.0003301488,0.0001224331,0.000161768,0.9843484,0.0009044071,0.0003918625,0.01323778],"study_design_scores_gemma":[0.0000438236,0.0005510528,0.002473025,0.000175661,0.00007488683,0.002588867,0.0001595147,0.001573553,0.9206893,0.0006304177,0.07098513,0.00005490748],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.4635044,0.00962521,0.4995797,0.001299299,0.0006271674,0.002490419,0.006659832,0.006574978,0.009638993],"genre_scores_gemma":[0.4885631,0.01384469,0.4508206,0.0003763748,0.0001792161,0.002349877,0.02026215,0.001486522,0.02211746],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002132272,"threshold_uncertainty_score":0.005457997,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01029627031217081,"score_gpt":0.2255703693197669,"score_spread":0.2152740990075961,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}