{"id":"W2006418616","doi":"10.1117/12.739631","title":"High-resolution single-molecule optical trapping measurements of transcription with basepair accuracy: instrumentation and methods","year":2007,"lang":"en","type":"article","venue":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","topic":"Orbital Angular Momentum in Optics","field":"Physics and Astronomy","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada; University of Alberta","funders":"National Science Foundation","keywords":"Biophysics; Trapping; DNA; Physics; Base pair; Chemistry; Nucleotide; Atomic physics; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005617076,0.0003559549,0.0003037091,0.0003350945,0.0003521281,0.0004198356,0.0009153163,0.0005387828,0.001258855],"category_scores_gemma":[0.0008601066,0.000269574,0.0001640161,0.0004652627,0.0004774978,0.0004173319,0.000306641,0.0008932707,0.000420819],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005324906,"about_ca_system_score_gemma":0.0003460825,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00064841,"about_ca_topic_score_gemma":0.001024074,"domain_scores_codex":[0.9994813,0.00007582007,0.0000285874,0.0001403051,0.0002340955,0.00003986736],"domain_scores_gemma":[0.9995283,0.0001826195,0.00009565456,0.00007794569,0.00008170212,0.0000337403],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000022858,0.00002064473,0.0002642112,0.00006309123,0.000004344879,0.00001377837,0.00003866312,0.0005840739,0.9920716,0.0007202473,0.00008285067,0.006113584],"study_design_scores_gemma":[0.00001078715,0.00005483639,0.001087571,0.000006192985,0.000006869033,0.0000767359,0.00001840153,0.008118898,0.9878462,0.0002537726,0.002501908,0.00001786306],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.372524,0.001814049,0.6192506,0.0004037323,0.0001042519,0.0004067017,0.001157155,0.001084942,0.003254643],"genre_scores_gemma":[0.5838092,0.001797829,0.4083559,0.0001616088,0.00005536922,0.0009460035,0.000679624,0.0001624156,0.004032059],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.001258855,"threshold_uncertainty_score":0.004211247,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01762661100233328,"score_gpt":0.257183053998033,"score_spread":0.2395564429956998,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}