{"id":"W2006450435","doi":"10.1128/iai.69.1.579-583.2001","title":"Mouse Toxicity and Cytokine Release by Verotoxin 1 B Subunit Mutants","year":2001,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Toxin Mechanisms and Immunotoxins","field":"Immunology and Microbiology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"Medical Research Council; Medical Research Council Canada; University of Toronto","keywords":"Biology; Cytotoxicity; Cytokine; Molecular biology; Mutant; Binding site; In vitro; Receptor; In vivo; Toxicity; Biochemistry; Immunology; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002042579,0.0006142731,0.0002628842,0.0003014544,0.0001060615,0.0002612847,0.0002041938,0.000519842,0.0007451792],"category_scores_gemma":[0.0001724043,0.0001830326,0.0003001186,0.0001586998,0.0002306668,0.0001589454,0.000132968,0.0007719988,0.0002109456],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002749462,"about_ca_system_score_gemma":0.00013409,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004920145,"about_ca_topic_score_gemma":0.000476691,"domain_scores_codex":[0.9996715,0.00008473443,0.00004154552,0.00005453103,0.00007106831,0.00007663693],"domain_scores_gemma":[0.9997136,0.00006480343,0.0001151495,0.00002920011,0.00001637798,0.00006095538],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001699726,0.00003619014,0.0001587578,0.000008300079,0.000004120378,0.00003031839,0.000005813025,0.00009459035,0.9992488,0.0000213819,0.000007403422,0.0002141854],"study_design_scores_gemma":[0.00003350765,0.001453655,0.00246075,0.000005072691,0.00001467293,0.000219016,0.00001357146,0.0007140804,0.9947865,0.00002729244,0.0002674875,0.00000418453],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985178,0.0003756715,0.0005273002,0.0000274928,0.00001012199,0.00001240428,0.000193206,0.00002759927,0.0003083572],"genre_scores_gemma":[0.9973852,0.0003486076,0.0007128557,0.00003188071,0.000006674681,0.00002147755,0.0005190504,0.00001895185,0.000955353],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007451792,"threshold_uncertainty_score":0.002492845,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01073449640719469,"score_gpt":0.2281199220375377,"score_spread":0.217385425630343,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}