{"id":"W2006512077","doi":"10.1111/j.1067-1927.2004.012113.x","title":"Connective tissue growth factor siRNA modulates mRNA levels for a subset of molecules in normal and TGF‐β1–stimulated porcine skin fibroblasts","year":2004,"lang":"en","type":"article","venue":"Wound Repair and Regeneration","topic":"Connective Tissue Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Bone and Joint Health Institute; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Calgary Foundation","keywords":"Transforming growth factor; Connective tissue; Messenger RNA; CTGF; Cell biology; Growth factor; Chemistry; Molecular biology; Biology; Pathology; Medicine; Gene; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001478305,0.000174151,0.0002125026,0.000114007,0.00008789425,0.00002409319,0.0000573263,0.0001816772,0.000008285528],"category_scores_gemma":[0.0001634888,0.0001573827,0.00005258972,0.0001140551,0.0001153265,0.00001801593,0.00006374283,0.00007013363,4.1294e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003376327,"about_ca_system_score_gemma":0.00007105171,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002752999,"about_ca_topic_score_gemma":0.0005891789,"domain_scores_codex":[0.9989383,0.00006213867,0.0002506567,0.0004099923,0.0001178676,0.0002210681],"domain_scores_gemma":[0.9994494,0.00003858506,0.00007791602,0.0001520197,0.0002048982,0.00007713492],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002669321,0.00006627297,0.006126635,0.0001080725,0.00006817619,0.000004272864,0.0003950993,0.001328496,0.9900941,0.0004497378,0.00002198728,0.001070217],"study_design_scores_gemma":[0.001992144,0.0009152754,0.07038186,0.00003354636,0.00001367901,0.00002016308,0.0000667398,0.001424675,0.9242287,0.0005944018,0.0001328309,0.000195995],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937587,0.00120489,0.00406354,0.0001499809,0.00004220254,0.0006269779,0.0001067451,0.00001538157,0.00003161424],"genre_scores_gemma":[0.9981562,0.00009568285,0.001287788,0.00001859511,0.00009200349,0.00003286032,0.0001753493,0.00002125535,0.000120243],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06586541,"threshold_uncertainty_score":0.6417879,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01613076939630257,"score_gpt":0.2784467600358622,"score_spread":0.2623159906395596,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}