{"id":"W2006514811","doi":"10.1016/j.yexcr.2011.06.004","title":"Inhibition of glycogen synthase kinase-3 enhances the differentiation and reduces the proliferation of adult human olfactory epithelium neural precursors","year":2011,"lang":"en","type":"article","venue":"Experimental Cell Research","topic":"Olfactory and Sensory Function Studies","field":"Neuroscience","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; Centre for Addiction and Mental Health; University of Toronto","funders":"Canadian Institutes of Health Research; University of Toronto; National Alliance for Research on Schizophrenia and Depression; Brain and Behavior Research Foundation","keywords":"Biology; GSK-3; Neurogenesis; Neural stem cell; Cell biology; Cell growth; Cellular differentiation; Neural cell; Glycogen synthase; Cell; Stem cell; Signal transduction; Biochemistry; Phosphorylation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001229882,0.0002071708,0.0002252694,0.0001745418,0.0001209592,0.0002554047,0.0001453737,0.0001756918,0.001532618],"category_scores_gemma":[0.0001447169,0.0001344621,0.0002005746,0.0001118963,0.0002048107,0.00009647354,0.0001337946,0.0004765931,0.000274502],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001825829,"about_ca_system_score_gemma":0.0003013027,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001207704,"about_ca_topic_score_gemma":0.001585308,"domain_scores_codex":[0.9999145,0.00001477812,0.000008421514,0.00001139502,0.0000204755,0.00003036768],"domain_scores_gemma":[0.9999355,0.00002197409,0.000008230308,0.000009105899,0.000004528814,0.00002065227],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006877612,0.00009831334,0.0002066619,0.00002826285,0.000008068127,0.00006872042,0.00001787249,0.00007802818,0.996998,0.0001068134,0.00008215365,0.001619423],"study_design_scores_gemma":[0.00007255223,0.0008543588,0.005870296,0.000003694841,0.00002292612,0.00021943,0.00003936986,0.0005032967,0.990905,0.00004644441,0.001459404,0.000003314789],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997971,0.0006854323,0.000285511,0.00004663623,0.00001804273,0.000007231372,0.0000810817,0.00002251265,0.0008824558],"genre_scores_gemma":[0.9972787,0.0005451349,0.0002363869,0.0000258547,0.000006804614,0.0000123977,0.0002298726,0.000008117762,0.001656831],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001532618,"threshold_uncertainty_score":0.005127132,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2435921086200765,"score_gpt":0.3465108885435207,"score_spread":0.1029187799234442,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}