{"id":"W2006531104","doi":"10.1111/j.0105-2896.2006.00361.x","title":"ATM‐dependent DNA damage surveillance in T‐cell development and leukemogenesis: the DSB connection","year":2006,"lang":"en","type":"review","venue":"Immunological Reviews","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Biology; Ataxia-telangiectasia; DNA damage; Antigen; DNA repair; T-cell receptor; Immune system; Cell biology; Genetics; Cancer research; Immunology; DNA; T cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001415188,0.0005291976,0.00135903,0.00005369731,0.0001075296,0.00004815269,0.0005155653,0.0005744025,0.00002115784],"category_scores_gemma":[0.0002561759,0.0003054524,0.0003257545,0.0001861954,0.00009629111,0.000003336128,0.0004223194,0.0003439057,0.00009389677],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001139071,"about_ca_system_score_gemma":0.0001515472,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001576822,"about_ca_topic_score_gemma":0.0000882103,"domain_scores_codex":[0.9966879,0.001005931,0.001011481,0.0007658664,0.0001449802,0.0003838731],"domain_scores_gemma":[0.9986493,0.00007754526,0.000477621,0.0007185554,0.00003230709,0.00004466308],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000007239583,0.00006063416,0.00000583846,0.00149128,0.00003482502,0.00001067374,0.000005280896,3.637934e-7,0.001450893,0.00002768058,0.0001352871,0.99677],"study_design_scores_gemma":[0.0001832192,0.00009567639,0.00006042821,0.001014995,0.00005309812,0.00004615738,0.000007451045,4.712853e-7,0.001509118,0.00001314513,0.9966357,0.000380557],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001931003,0.9955626,0.00008137089,0.00001206894,0.0001891792,0.001504726,0.00001005497,0.00002068704,0.0006883055],"genre_scores_gemma":[0.0001786067,0.9971609,0.0004185791,0.00006922754,0.00008266077,0.0005802207,0.0002564972,0.00003686867,0.001216425],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9965004,"threshold_uncertainty_score":0.9999397,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04234753624877697,"score_gpt":0.2950902510797064,"score_spread":0.2527427148309295,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}