{"id":"W2006533418","doi":"10.1002/jnr.21789","title":"Adenosine produced by neurons is metabolized to hypoxanthine by astrocytes","year":2008,"lang":"en","type":"article","venue":"Journal of Neuroscience Research","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Hypoxanthine; NMDA receptor; Adenosine; Inosine; Astrocyte; Purine nucleoside phosphorylase; Neurotoxicity; Glutamate receptor; Neuroglia; Chemistry; Nucleoside; Neuron; Extracellular; Biology; Biochemistry; Internal medicine; Cell biology; Endocrinology; Purine; Receptor; Neuroscience; Central nervous system; Medicine; Toxicity; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008796012,0.0001388254,0.000215851,0.0001900035,0.0003066252,0.00005569604,0.0007274486,0.00006047549,0.00002311099],"category_scores_gemma":[0.0009800527,0.0001109928,0.00009568175,0.00067805,0.0002428972,0.00002257289,0.0002187914,0.0003990593,0.000008562876],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001404163,"about_ca_system_score_gemma":0.0002628985,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000100044,"about_ca_topic_score_gemma":1.619195e-7,"domain_scores_codex":[0.9975477,0.0002100446,0.0003578642,0.0003807941,0.0009846704,0.0005188529],"domain_scores_gemma":[0.9986719,0.00004761446,0.0001276657,0.0002929408,0.0005057093,0.0003541115],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009697672,0.00008668592,0.0004631934,0.000002559112,0.000004556158,0.00003007158,0.00002825383,0.00002066489,0.6823288,0.000001257348,0.316837,0.0001000168],"study_design_scores_gemma":[0.0003848085,0.001155105,0.0008028032,0.000008194975,0.00000578492,0.0002636565,0.00002039753,0.00002928969,0.8183571,0.00000310339,0.1788733,0.00009641893],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905987,0.004028264,0.0006137063,0.004341191,0.0001798935,0.000143907,0.00001976659,0.000004358435,0.00007016863],"genre_scores_gemma":[0.9941035,0.001530554,0.0003279336,0.001154167,0.0003662855,0.000004917546,0.000002442526,0.00002132971,0.002488889],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1379637,"threshold_uncertainty_score":0.4526156,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07210515981705364,"score_gpt":0.3682856468700043,"score_spread":0.2961804870529507,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}