{"id":"W2006567912","doi":"10.1007/s12016-014-8419-x","title":"Genetics in PBC: What Do the “Risk Genes” Teach Us?","year":2014,"lang":"en","type":"review","venue":"Clinical Reviews in Allergy & Immunology","topic":"Liver Diseases and Immunity","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Disease; Biology; Genome-wide association study; Immune system; Phenotype; Primary biliary cirrhosis; Human leukocyte antigen; Immunology; Genetic association; Genetics; Gene; Genotype; Medicine; Single-nucleotide polymorphism; Pathology; Antigen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001425345,0.0008855867,0.00210684,0.001545552,0.0002930217,0.001323134,0.001236553,0.002387692,0.002268326],"category_scores_gemma":[0.001971172,0.000355125,0.0007710948,0.001503483,0.001200871,0.002229469,0.0008405682,0.003509784,0.001142055],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008455238,"about_ca_system_score_gemma":0.001326802,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00179779,"about_ca_topic_score_gemma":0.002602772,"domain_scores_codex":[0.9996397,0.0001050282,0.00004815697,0.00005694112,0.0001136262,0.00003643109],"domain_scores_gemma":[0.9989437,0.0006849991,0.00009315601,0.00002602061,0.0001794116,0.00007271843],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001389328,0.00007207684,0.001294644,0.01004053,0.0002485957,0.0006199452,0.0001017127,0.0004398238,0.0009738645,0.01130291,0.0802351,0.8945318],"study_design_scores_gemma":[0.00006910574,0.00009267665,0.002553305,0.01018408,0.0003664762,0.003306575,0.0001741736,0.0001966423,0.0002850716,0.01496543,0.9677446,0.0000617355],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006636281,0.9972467,0.0001084872,0.001815884,0.00044167,0.000001177344,0.00001017066,0.000004119847,0.0003053988],"genre_scores_gemma":[0.0005971689,0.9969071,0.0001560688,0.001090299,0.00104693,0.000002559508,0.00001525541,0.000001435955,0.000183178],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002387692,"threshold_uncertainty_score":0.007588267,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1111142616149754,"score_gpt":0.4360573835289489,"score_spread":0.3249431219139736,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}