{"id":"W2006581520","doi":"10.3389/fendo.2013.00056","title":"Activation of PAC1 Receptors in Rat Cerebellar Granule Cells Stimulates Both Calcium Mobilization from Intracellular Stores and Calcium Influx through N-Type Calcium Channels","year":2013,"lang":"en","type":"article","venue":"Frontiers in Endocrinology","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Interreg; Langley Research Center; Région Normandie; Institut National de la Santé et de la Recherche Médicale; Institut national de la recherche scientifique","keywords":"Calcium; Calcium in biology; Granule (geology); Voltage-dependent calcium channel; Receptor; T-type calcium channel; Mobilization; Chemistry; Intracellular; Granule cell; Calcium signaling; Cell biology; Neuroscience; Biophysics; Biology; Biochemistry; Central nervous system; Dentate gyrus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001349942,0.0006995478,0.0007579875,0.000315243,0.0002410185,0.0005093184,0.000448278,0.0003885775,0.001653801],"category_scores_gemma":[0.000242725,0.0002869252,0.0004114414,0.0004790746,0.0002803168,0.0004015586,0.0002418795,0.0009130721,0.0008533566],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006346666,"about_ca_system_score_gemma":0.0003967629,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002421031,"about_ca_topic_score_gemma":0.004848648,"domain_scores_codex":[0.9997206,0.00002166018,0.00002184743,0.00007471852,0.00007591682,0.00008525242],"domain_scores_gemma":[0.9998902,0.00001254398,0.00004309596,0.00001697884,0.00001295518,0.00002414704],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001877804,0.00003066645,0.0001700556,0.0001139314,0.00001011325,0.0001894985,0.00003414938,0.0000519922,0.996821,0.00006877522,0.00007923895,0.002242787],"study_design_scores_gemma":[0.00008814736,0.001210944,0.01476029,0.00002783713,0.0001240078,0.001372594,0.00009312898,0.0008058132,0.9725495,0.00008237145,0.008865683,0.0000197385],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98071,0.01394015,0.00229024,0.0001971047,0.00006285936,0.00006744544,0.0008146961,0.0002015924,0.001715828],"genre_scores_gemma":[0.9799116,0.01001929,0.004603893,0.0001074397,0.00007100272,0.0001479463,0.001732626,0.0000343596,0.003371842],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002421031,"threshold_uncertainty_score":0.005532503,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03078099802564751,"score_gpt":0.2607492237182785,"score_spread":0.229968225692631,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}