{"id":"W2006588522","doi":"10.1186/1756-6606-3-38","title":"The modulation of TRPM7 currents by nafamostat mesilate depends directly upon extracellular concentrations of divalent cations","year":2010,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Magnesium in Health and Disease","field":"Nursing","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Robarts Clinical Trials; Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre; Western University","funders":"National Institute of Neurological Disorders and Stroke; Robarts Research Institute; Canadian Institutes of Health Research; Core Research for Evolutional Science and Technology; University of Toronto; Canadian Stroke Network; Heart and Stroke Foundation of Canada","keywords":"Extracellular; Divalent; TRPM7; Chemistry; Biophysics; Intracellular; Biochemistry; Transient receptor potential channel; Receptor; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009773274,0.0002503963,0.0002277332,0.00008973922,0.000101737,0.0001691335,0.000146046,0.0001922149,0.0007839033],"category_scores_gemma":[0.0001276339,0.00007570358,0.0002070454,0.00006534027,0.0001476093,0.0001493752,0.0001121064,0.0003692028,0.0002229984],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000147438,"about_ca_system_score_gemma":0.0001463791,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002303931,"about_ca_topic_score_gemma":0.000435461,"domain_scores_codex":[0.9999282,0.0000109794,0.00001314681,0.00001508413,0.00001585193,0.00001676657],"domain_scores_gemma":[0.999945,0.00001469007,0.00001602937,0.000006224755,0.000008418464,0.000009616352],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007930882,0.000006515921,0.00009124585,0.00003352431,0.000003104012,0.00002138953,0.000004232238,0.00001406687,0.9988738,0.00002617024,0.00001483943,0.0008319038],"study_design_scores_gemma":[0.00001414909,0.0002063453,0.001926881,0.000004617085,0.00001186994,0.0001391979,0.000010008,0.0001932381,0.9959292,0.00001876726,0.001543406,0.000002316081],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906939,0.004507396,0.002452847,0.0001836099,0.00005170141,0.00004567535,0.0003203236,0.00005913017,0.001685392],"genre_scores_gemma":[0.9931982,0.002848302,0.002668583,0.00007739306,0.00002047929,0.00006096607,0.0003905502,0.00000975308,0.0007257911],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007839033,"threshold_uncertainty_score":0.002622366,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007950134268533644,"score_gpt":0.281010733661455,"score_spread":0.2730605993929214,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}