{"id":"W2006591356","doi":"10.1002/gene.20074","title":"Cre recombinase specificity defined by the <i>tau</i> locus","year":2004,"lang":"en","type":"article","venue":"genesis","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute","funders":"","keywords":"Cre recombinase; Biology; Transgene; Recombinase; Locus (genetics); Genetically modified mouse; Allele; Genetics; Gene targeting; Cre-Lox recombination; Molecular biology; Offspring; Reporter gene; Cell biology; Gene; Recombination; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001511891,0.0002590674,0.0002079355,0.00005237073,0.0005039962,0.0001086552,0.0005864736,0.00006722192,0.0002011645],"category_scores_gemma":[0.0003255707,0.0001891093,0.0001406481,0.0004650705,0.0001238535,0.0001013924,0.0001463335,0.0001595356,0.0006570941],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004354759,"about_ca_system_score_gemma":0.00005252853,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006968036,"about_ca_topic_score_gemma":0.00001387708,"domain_scores_codex":[0.9979678,0.0001854792,0.000278383,0.0006646751,0.0004238585,0.0004798481],"domain_scores_gemma":[0.9987726,0.0003351867,0.0001087961,0.000598464,0.00003064781,0.0001543658],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002839259,0.0002141712,0.00002090122,0.000005966795,0.000002376954,0.00007432527,0.0000411395,0.0001040598,0.9898456,0.00410756,0.004365433,0.001190126],"study_design_scores_gemma":[0.0005397589,0.0001401419,0.0001668654,0.000006048743,0.00002018672,0.0001181601,0.00002286812,0.00001460807,0.9849604,0.0008287292,0.01296519,0.0002169869],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937405,0.0001345935,0.001764673,0.001704511,0.0008414926,0.0002839779,0.00006539754,0.0001862855,0.001278584],"genre_scores_gemma":[0.9941161,0.0002526795,0.0001243314,0.004491489,0.0001027285,0.00003370718,0.000002165988,0.00005412316,0.0008226866],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008599753,"threshold_uncertainty_score":0.8445835,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03137504240883405,"score_gpt":0.2297348176807119,"score_spread":0.1983597752718778,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}