{"id":"W2006606320","doi":"10.1038/cgt.2008.49","title":"Bystander effect in glioblastoma cells with a predominant cytoplasmic localization of connexin43","year":2008,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Hôtel-Dieu de Québec; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research","keywords":"Bystander effect; Gap junction; Cell culture; Cell biology; Connexin; HeLa; Transfection; Cancer research; Downregulation and upregulation; Chemistry; Cytoplasm; Cell; Kinase; Intracellular; Gene silencing; Ganciclovir; Small interfering RNA; Biology; Gene; Virology; Virus; Immunology; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008519839,0.0001396245,0.0002071494,0.00004905696,0.00003282698,0.00000233629,0.00009544443,0.00011006,0.00006059567],"category_scores_gemma":[0.00000378594,0.0001029132,0.00004501752,0.0001157183,0.0001327758,0.000002010026,0.0000175254,0.00004518528,0.000001496647],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002030891,"about_ca_system_score_gemma":0.0001143655,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007513316,"about_ca_topic_score_gemma":0.0002806514,"domain_scores_codex":[0.9992674,0.00007599234,0.0001599618,0.0002539685,0.00006416312,0.0001785089],"domain_scores_gemma":[0.9996007,0.00001259167,0.00007841105,0.0002172097,0.00005743228,0.00003367406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003305152,0.0000630689,0.01730261,0.00001453733,0.00005522267,0.00001076587,0.0001614318,0.001896222,0.9742271,0.000007316413,0.000265925,0.002690654],"study_design_scores_gemma":[0.002759104,0.002391486,0.001438554,0.00001892258,0.000005309534,0.00002192149,0.00001446615,0.0002155124,0.9870898,0.000006562543,0.005894023,0.000144375],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938083,0.003926383,0.001807752,0.00002702894,0.00007346363,0.0002751453,0.00001777175,0.000005992626,0.00005820531],"genre_scores_gemma":[0.995134,0.004339518,0.00003521018,0.0002003098,0.00007852494,0.00006123445,0.00001344137,0.00001989198,0.0001178907],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01586405,"threshold_uncertainty_score":0.4196677,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007593813026047828,"score_gpt":0.2324842981733679,"score_spread":0.22489048514732,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}