{"id":"W2006606320","doi":"10.1038/cgt.2008.49","title":"Bystander effect in glioblastoma cells with a predominant cytoplasmic localization of connexin43","year":2008,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Hôtel-Dieu de Québec; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research","keywords":"Bystander effect; Gap junction; Cell culture; Cell biology; Connexin; HeLa; Transfection; Cancer research; Downregulation and upregulation; Chemistry; Cytoplasm; Cell; Kinase; Intracellular; Gene silencing; Ganciclovir; Small interfering RNA; Biology; Gene; Virology; Virus; Immunology; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003299164,0.0004978469,0.0009341313,0.0003669766,0.0003482402,0.0003371141,0.0002000096,0.0006326627,0.002316579],"category_scores_gemma":[0.0002206293,0.0001558729,0.0004034915,0.0003081003,0.0002650779,0.0002580881,0.0002296019,0.0005893178,0.000370562],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003775008,"about_ca_system_score_gemma":0.0003180171,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003046875,"about_ca_topic_score_gemma":0.002044775,"domain_scores_codex":[0.9997395,0.00005750192,0.00001830651,0.00003212304,0.00005345557,0.00009899868],"domain_scores_gemma":[0.9998226,0.00006848734,0.00002140254,0.0000369691,0.00001517178,0.00003543027],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000471015,0.0001340849,0.0001739812,0.00004855719,0.00002358918,0.0002966622,0.00008520818,0.0001272438,0.9965658,0.0004822104,0.0001544772,0.001437186],"study_design_scores_gemma":[0.0001156306,0.001399011,0.003507648,0.000004928015,0.00005734641,0.0005532606,0.00007188222,0.001179065,0.9911503,0.000154439,0.00179994,0.000006603695],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959385,0.0009412073,0.0008746156,0.0001114864,0.00006209712,0.0000323156,0.0001558695,0.00008923549,0.001794607],"genre_scores_gemma":[0.9974267,0.0004355992,0.0003369811,0.00003762491,0.00001898424,0.00003038245,0.0001066207,0.0000154315,0.001591654],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003046875,"threshold_uncertainty_score":0.007749677,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007593813026047828,"score_gpt":0.2324842981733679,"score_spread":0.22489048514732,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}