{"id":"W2006703412","doi":"10.1016/s0143-4160(02)00093-3","title":"Xestospongin C is a potent inhibitor of SERCA at a vertebrate synapse","year":2002,"lang":"en","type":"article","venue":"Cell Calcium","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":45,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"SERCA; Thapsigargin; Ryanodine receptor; Endoplasmic reticulum; Chemistry; Biophysics; Adenosine; Internal medicine; Inositol; Neuromuscular junction; Endocrinology; Synapse; Cell biology; ATPase; Receptor; Neuroscience; Biology; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000189966,0.0003066097,0.0002387831,0.0001655857,0.0002435289,0.0002014213,0.0002083538,0.00028546,0.001374553],"category_scores_gemma":[0.0001718137,0.000119435,0.0001989646,0.0001537259,0.0002926683,0.0001686822,0.0001628615,0.0005314322,0.0002129101],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002768391,"about_ca_system_score_gemma":0.0004161181,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001324732,"about_ca_topic_score_gemma":0.003411989,"domain_scores_codex":[0.999929,0.000008435985,0.00000532903,0.00001086412,0.00001994833,0.00002649909],"domain_scores_gemma":[0.9999031,0.00002556747,0.00001316078,0.000009757769,0.000008317261,0.0000401297],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003459195,0.00002547563,0.0002331366,0.00006309237,0.00001184037,0.0001322209,0.000009403931,0.00008361881,0.9968057,0.0001572145,0.00009663802,0.002035849],"study_design_scores_gemma":[0.0001281002,0.001043081,0.01092164,0.00001305346,0.00002890373,0.0008425949,0.00002330585,0.0005838664,0.9817532,0.00007882869,0.004576559,0.00000677115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988705,0.003490638,0.001955257,0.0001554325,0.00005735116,0.0000929676,0.0003513161,0.00004879911,0.005143174],"genre_scores_gemma":[0.9908963,0.003265652,0.002227955,0.00009277491,0.00003808687,0.0000361388,0.000612249,0.00001115095,0.002819726],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001374553,"threshold_uncertainty_score":0.00459832,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08328783381546347,"score_gpt":0.3025871860649887,"score_spread":0.2192993522495252,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}