{"id":"W2006770834","doi":"10.1046/j.1524-475x.2003.11505.x","title":"Proliferation of peripheral blood mononuclear cells is suppressed by the indoleamine 2,3‐dioxygenase expression of interferon‐γ–treated skin cells in a co‐culture system","year":2003,"lang":"en","type":"article","venue":"Wound Repair and Regeneration","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Sick Kids Foundation","keywords":"Indoleamine 2,3-dioxygenase; Peripheral blood mononuclear cell; Kynurenine; Interferon gamma; Immune system; Interferon; Immunology; Cytokine; Monocyte; Human skin; Cell culture; Biology; Tryptophan; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001709944,0.0001614412,0.0001965813,0.00006956118,0.0001016677,0.00004970018,0.00008756647,0.0001415265,0.00001914457],"category_scores_gemma":[0.00002278346,0.0001017607,0.00007274188,0.0001939357,0.0001147209,0.000135199,0.00001799793,0.0001259859,0.000002049306],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000233645,"about_ca_system_score_gemma":0.00002562716,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002780596,"about_ca_topic_score_gemma":0.0000153163,"domain_scores_codex":[0.9986291,0.0003158847,0.0003657932,0.0003419357,0.0002015069,0.0001457702],"domain_scores_gemma":[0.9995305,0.0000340313,0.0001368743,0.0002206962,0.00003871472,0.00003916669],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000887159,0.000176199,0.00004510227,0.0001898011,0.000007272851,0.000002575411,0.0025076,0.0002619857,0.9928671,0.0002538027,0.003551214,0.00004867395],"study_design_scores_gemma":[0.0008360085,0.0002319493,0.00002979856,0.0001084415,0.00000995212,0.0000107098,0.0007507094,0.003651925,0.9936211,0.00001680074,0.0006208479,0.0001118101],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979461,0.0006013602,0.0001137817,0.00003309099,0.00009438332,0.0005596534,0.00004607759,0.0000493974,0.0005561111],"genre_scores_gemma":[0.9984804,0.0001013132,0.0000966825,0.00006993744,0.00002808941,0.0000273496,0.00001363143,0.00001717738,0.001165433],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003389939,"threshold_uncertainty_score":0.414968,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008788480305289649,"score_gpt":0.2147096819185366,"score_spread":0.205921201613247,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}