{"id":"W2006773042","doi":"10.1016/s0006-2952(02)01346-1","title":"Enhanced activity of liposomal polymyxin B against Pseudomonas aeruginosa in a rat model of lung infection","year":2002,"lang":"en","type":"article","venue":"Biochemical Pharmacology","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":158,"is_retracted":false,"has_abstract":false,"ca_institutions":"Laurentian University","funders":"","keywords":"Polymyxin B; Polymyxin; Pseudomonas aeruginosa; Liposome; Lung; Microbiology; Pharmacology; Saline; Antibiotics; Chemistry; Medicine; Biology; Bacteria; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003643066,0.0006009655,0.0005826348,0.0004436446,0.0002017817,0.0002657054,0.0003350481,0.0005359856,0.001086523],"category_scores_gemma":[0.0002898609,0.0002878787,0.0002984955,0.0002030711,0.0005780537,0.0005232188,0.0002115174,0.001119214,0.0002746989],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003067308,"about_ca_system_score_gemma":0.0003955741,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009828288,"about_ca_topic_score_gemma":0.0007504498,"domain_scores_codex":[0.9998401,0.00003829013,0.000008798376,0.00002319616,0.00002766372,0.00006187353],"domain_scores_gemma":[0.9996936,0.00006551262,0.00006352729,0.00004252065,0.00003429803,0.0001005015],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003464683,0.0003446015,0.0001715546,0.00008606124,0.00001162601,0.0001018517,0.00002417369,0.0001679488,0.9930031,0.0001185812,0.00004240587,0.002463416],"study_design_scores_gemma":[0.0001347108,0.004454636,0.001985975,0.00001165503,0.0000434765,0.000123475,0.00002582386,0.0006783874,0.9920506,0.0000614073,0.0004216188,0.000008222632],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957659,0.001601401,0.001725513,0.0001291643,0.00004145316,0.00003267692,0.0001228771,0.00008047915,0.0005005304],"genre_scores_gemma":[0.9952117,0.001312863,0.001360115,0.0000479591,0.00003345254,0.00004819794,0.0001876705,0.00001660765,0.00178146],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001086523,"threshold_uncertainty_score":0.00363481,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01359737823682608,"score_gpt":0.2746383498643589,"score_spread":0.2610409716275328,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}