{"id":"W2006789966","doi":"10.1016/j.cell.2012.01.026","title":"Innate Immunity to TB: A Druggable Balancing Act","year":2012,"lang":"en","type":"letter","venue":"Cell","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Biology; Druggability; Innate immune system; Immunity; Virology; Immunology; Computational biology; Genetics; Immune system; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00550801,0.001264567,0.002529226,0.0008928618,0.005223668,0.005957128,0.002059483,0.08374158,0.006916155],"category_scores_gemma":[0.03309804,0.001052065,0.001420194,0.0007184935,0.008030608,0.007250466,0.004418869,0.07976344,0.005647513],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.006252893,"about_ca_system_score_gemma":0.005932984,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003566569,"about_ca_topic_score_gemma":0.008169509,"domain_scores_codex":[0.994003,0.002318847,0.000608,0.0007217785,0.001613398,0.0007349584],"domain_scores_gemma":[0.9837433,0.009883702,0.001031038,0.0005655795,0.002053166,0.002723221],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007247701,0.00004468208,0.0004175189,0.00007464017,0.00002348113,0.001316275,0.000143641,0.00005938848,0.0002375702,0.007401409,0.9769932,0.01321577],"study_design_scores_gemma":[0.0003291702,0.0001236682,0.001024318,0.000505056,0.0000756245,0.003132541,0.0004746944,0.0007439189,0.0003733336,0.0423668,0.9507582,0.00009270701],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"editorial","genre_scores_codex":[0.0001217407,0.001267857,0.00006863529,0.9882843,0.009518214,0.000003416674,0.000009346071,0.000008368047,0.0007180544],"genre_scores_gemma":[0.002598817,0.001261759,0.0002198838,0.9334658,0.05868547,0.00002217118,0.00001016936,0.00001093502,0.003725088],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.08374158,"threshold_uncertainty_score":0.04536819,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03204042209020153,"score_gpt":0.3158745072655251,"score_spread":0.2838340851753235,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}