{"id":"W2006789966","doi":"10.1016/j.cell.2012.01.026","title":"Innate Immunity to TB: A Druggable Balancing Act","year":2012,"lang":"en","type":"letter","venue":"Cell","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Biology; Druggability; Innate immune system; Immunity; Virology; Immunology; Computational biology; Genetics; Immune system; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000826113,0.0002969632,0.0007656946,0.0002643373,0.00008820222,0.0000176924,0.0002922534,0.0007912593,0.00158192],"category_scores_gemma":[0.0005272602,0.0002386586,0.0001998548,0.000207305,0.00005433104,0.00005240902,0.0002267962,0.003323041,0.004733236],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002237677,"about_ca_system_score_gemma":0.0001820795,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001046906,"about_ca_topic_score_gemma":0.00001351783,"domain_scores_codex":[0.9974686,0.0003190968,0.0003324594,0.0003592049,0.0003121304,0.001208541],"domain_scores_gemma":[0.9981939,0.0003898824,0.00008671994,0.0008446206,0.00009525007,0.0003895856],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004212372,0.00004223828,0.002021214,0.0004349893,0.00005874702,0.0002160294,0.0001285139,8.8328e-7,0.004546929,6.60702e-7,0.9919729,0.0005348012],"study_design_scores_gemma":[0.0003712256,0.0001468299,0.003105806,0.0001237019,0.00006924757,0.00004775465,0.00001589191,0.00002123369,0.002174239,0.00001856028,0.9936846,0.0002209216],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.02493417,0.001589578,0.0000359368,0.8468635,0.00060064,0.0006897372,0.00003811642,0.0001166114,0.1251317],"genre_scores_gemma":[0.01945624,0.0002194668,0.0005013953,0.9230075,0.005534268,0.00006803377,0.000606253,0.00008604676,0.05052079],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.07614402,"threshold_uncertainty_score":0.9993308,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03204042209020153,"score_gpt":0.3158745072655251,"score_spread":0.2838340851753235,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}