{"id":"W2006824856","doi":"10.1371/journal.pbio.1000211","title":"From Molecules to Behavior: Organismal-Level Regulation of Ion Channel Trafficking","year":2009,"lang":"en","type":"article","venue":"PLoS Biology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Exocytosis; Transmembrane protein; Biology; Membrane protein; Cell biology; Endocytosis; Ion channel; Membrane transport; Endoplasmic reticulum; Cell membrane; Transport protein; Transmembrane channels; Membrane; Cell; Biochemistry; Voltage-gated ion channel; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006531171,0.0001221484,0.0001466603,0.00008025299,0.00004575492,0.00000606952,0.000103221,0.0002269115,0.00005619487],"category_scores_gemma":[0.00006054134,0.0001184133,0.00005742534,0.0001019846,0.00003015403,0.000003413344,0.00003086855,0.00004509282,0.00001657882],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001283181,"about_ca_system_score_gemma":0.00002110983,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001488994,"about_ca_topic_score_gemma":0.000007852661,"domain_scores_codex":[0.999191,0.0000520524,0.0002208149,0.0003064378,0.00007185142,0.0001578656],"domain_scores_gemma":[0.9995151,0.000007687331,0.00009236609,0.0002110761,0.0001139708,0.00005976712],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009095099,0.0001022129,0.000262252,0.000001916379,0.00001567382,3.002961e-7,0.0001209297,0.0003131431,0.9935796,0.0002063374,0.000368355,0.004938285],"study_design_scores_gemma":[0.0003879571,0.0006207778,0.03115714,0.00001148599,0.00002428127,0.000003227958,0.00007212802,0.0006176088,0.9649896,0.000592462,0.001356074,0.0001672378],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9740173,0.0000698527,0.02460073,0.0003961161,0.0003741063,0.0002126531,0.00004988747,0.00002473564,0.0002545867],"genre_scores_gemma":[0.9969805,0.00001287185,0.001082465,0.0003304424,0.0006905731,0.00001259107,0.0007250331,0.00001230304,0.0001532236],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03089489,"threshold_uncertainty_score":0.4828754,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02991232609801368,"score_gpt":0.2592317686758235,"score_spread":0.2293194425778099,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}