{"id":"W2006841412","doi":"10.1016/j.tree.2010.05.003","title":"Environmental duress and epistasis: how does stress affect the strength of selection on new mutations?","year":2010,"lang":"en","type":"review","venue":"Trends in Ecology & Evolution","topic":"Evolution and Genetic Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":209,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; University of Toronto","funders":"","keywords":"Selection (genetic algorithm); Geneticist; Affect (linguistics); Epistasis; Perspective (graphical); Natural selection; Empirical evidence; Cognitive psychology; Genetic Fitness; Stress (linguistics); Mutation; Perception; Biology; Evolutionary biology; Psychology; Genetics; Computer science; Artificial intelligence; Communication; Gene; Epistemology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001896283,0.0002976376,0.00047905,0.0002414478,0.0001018392,0.00001375839,0.0001862694,0.0006724627,0.00004323977],"category_scores_gemma":[0.00006221735,0.0002072488,0.0001720962,0.0001747228,0.0002702406,0.000004629488,0.00008013183,0.0004010358,0.000002932276],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001063936,"about_ca_system_score_gemma":0.0001328599,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003008017,"about_ca_topic_score_gemma":0.004513647,"domain_scores_codex":[0.9985403,0.0003252744,0.0003218573,0.0004562359,0.0001123979,0.0002438735],"domain_scores_gemma":[0.999213,0.00006985355,0.0003344378,0.0003094744,0.00001378193,0.0000595005],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005332557,0.0003478416,0.00799689,0.0005078343,0.0002132374,0.000001563181,0.00007042245,0.0001923314,0.0005638812,0.0004136351,0.0008473883,0.9887916],"study_design_scores_gemma":[0.002453875,0.002251604,0.2981879,0.001077747,0.001499956,0.0001931517,0.0003029872,0.001083812,0.0005541564,0.0004623046,0.6905447,0.001387806],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.09258241,0.9050122,0.0002218019,0.0002409709,0.0006964328,0.0006165228,0.000432213,0.00002028442,0.0001771173],"genre_scores_gemma":[0.3088502,0.68838,0.000165714,0.00001302884,0.0001999349,0.0000727087,0.00101302,0.00003048424,0.001274966],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9874039,"threshold_uncertainty_score":0.8451361,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0099192477334005,"score_gpt":0.2834342154208532,"score_spread":0.2735149676874528,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}