{"id":"W2006883921","doi":"10.1136/gut.2008.165738","title":"Steroid-sparing properties of sargramostim in patients with corticosteroid-dependent Crohn’s disease: a randomised, double-blind, placebo-controlled, phase 2 study","year":2009,"lang":"en","type":"article","venue":"Gut","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; University of Alberta","funders":"","keywords":"Medicine; Corticosteroid; Placebo; Clinical endpoint; Prednisone; Granulocyte macrophage colony-stimulating factor; Internal medicine; Crohn's disease; Surgery; Gastroenterology; Clinical trial; Disease; Pathology; Cytokine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002239718,0.001621189,0.004302335,0.0005061298,0.0003646259,0.00090378,0.001020579,0.002479917,0.005660963],"category_scores_gemma":[0.002232314,0.0007644705,0.001829943,0.0005318332,0.001665119,0.0009442255,0.0003718102,0.0021458,0.0009954353],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005671338,"about_ca_system_score_gemma":0.001114947,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000420658,"about_ca_topic_score_gemma":0.0007954862,"domain_scores_codex":[0.9988748,0.0006712292,0.00009773171,0.0001457688,0.00007969375,0.0001307737],"domain_scores_gemma":[0.9982079,0.0006435486,0.0004214496,0.0001328279,0.0001102672,0.0004839155],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9768187,0.007139915,0.000521515,0.0006507197,0.0003997675,0.00005827623,0.00004952721,0.0001226201,0.003624168,0.0000364441,0.0002371114,0.01034136],"study_design_scores_gemma":[0.9176928,0.08047058,0.001036034,0.00001607497,0.0001445535,0.00003379391,0.000009824803,0.00008550362,0.0002284282,0.00002289338,0.0002527652,0.000006686197],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899548,0.0053491,0.000345486,0.0004272161,0.0003656282,0.002283929,0.0003567031,0.00006030443,0.000856919],"genre_scores_gemma":[0.9873813,0.003711698,0.001355595,0.0009850829,0.0007914933,0.003640616,0.000616972,0.00001496563,0.00150225],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005660963,"threshold_uncertainty_score":0.01893777,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01389563433298244,"score_gpt":0.2535015915021935,"score_spread":0.2396059571692111,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}