{"id":"W2006919432","doi":"10.1016/j.jprot.2012.09.038","title":"Transcriptional divergence plays a role in the rewiring of protein interaction networks after gene duplication","year":2012,"lang":"en","type":"article","venue":"Journal of Proteomics","topic":"Bioinformatics and Genomic Networks","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health; Fonds de Recherche du Québec - Santé; National Institute for Health and Care Research","keywords":"Gene duplication; Functional divergence; Biology; Gene; Genetics; Alternative splicing; Exon; Proteome; Computational biology; Regulation of gene expression; Transcriptional regulation; Gene family; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006147518,0.00006770228,0.00009065041,0.00003531248,0.00002298744,0.00001207066,0.00014713,0.00008787283,0.000006541728],"category_scores_gemma":[0.0000166485,0.00004946042,0.00007547243,0.00005643993,0.00002346551,0.00002247033,0.0000239612,0.0001755049,7.309874e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001826029,"about_ca_system_score_gemma":0.00002686223,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004205402,"about_ca_topic_score_gemma":0.000005504147,"domain_scores_codex":[0.9993117,0.00004087615,0.0003697272,0.00004848655,0.0001015458,0.0001276528],"domain_scores_gemma":[0.9994707,0.000005557471,0.0003047175,0.0001122551,0.00007508172,0.00003168354],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006073363,0.0001474553,0.008615199,0.00002702306,0.00004493634,8.29468e-7,0.001000648,0.006749747,0.9794449,0.0002678877,0.00008475777,0.003009237],"study_design_scores_gemma":[0.004015683,0.001901425,0.2367686,0.000591228,0.0001870554,0.000926366,0.002747662,0.03865778,0.695274,0.002643416,0.01530928,0.0009774871],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9149314,0.001152251,0.08340882,0.00009125978,0.0001132205,0.0002258422,0.000002936149,5.886751e-7,0.00007372965],"genre_scores_gemma":[0.9926086,0.0001180777,0.006697557,0.0000742824,0.0004528314,0.00002293189,0.000006764036,0.000005636979,0.00001332363],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2841709,"threshold_uncertainty_score":0.2016938,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008699252065041168,"score_gpt":0.2261487905721027,"score_spread":0.2174495385070616,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}