{"id":"W2006920020","doi":"10.1371/journal.pcbi.1003239","title":"Polycation-π Interactions Are a Driving Force for Molecular Recognition by an Intrinsically Disordered Oncoprotein Family","year":2013,"lang":"en","type":"article","venue":"PLoS Computational Biology","topic":"Protein Structure and Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Vlaamse regering; Universiteit Gent; Fonds Wetenschappelijk Onderzoek; Canada Research Chairs; Compute Canada","keywords":"Intrinsically disordered proteins; Molecular recognition; Context (archaeology); Chemistry; Protein–protein interaction; Computational biology; Biophysics; Physics; Biology; Biochemistry; Molecule","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004763059,0.0001546827,0.0001452762,0.00005572081,0.0001171251,0.00003617643,0.000150026,0.000150116,0.00002258161],"category_scores_gemma":[0.0001565508,0.0001544401,0.00007206455,0.00006861489,0.00006905323,0.0000174497,0.00005508539,0.00008880659,0.00001872707],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002187186,"about_ca_system_score_gemma":0.00005935103,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003431466,"about_ca_topic_score_gemma":0.0000324486,"domain_scores_codex":[0.9990309,0.00007590482,0.0002408923,0.0003797891,0.00006804649,0.0002044179],"domain_scores_gemma":[0.999229,0.00005702558,0.0001486608,0.0001618421,0.0003225728,0.00008086587],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.00005154134,0.0001347068,0.000703099,0.00001279067,0.00009040861,2.521393e-7,0.00002088185,0.0005157517,0.973596,0.0007163265,0.0006604033,0.02349779],"study_design_scores_gemma":[0.005100537,0.00385572,0.02051783,0.0001231853,0.0001617427,0.00006433923,0.0005415854,0.1628506,0.2685873,0.5210639,0.0149055,0.002227707],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6386544,0.0001039919,0.3598902,0.0004796389,0.00006919569,0.0005535269,0.0001274894,0.00002393454,0.00009771781],"genre_scores_gemma":[0.9610236,0.000008676366,0.03098108,0.0009260943,0.0001471776,0.0004957328,0.006320158,0.00002366945,0.00007384709],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7050087,"threshold_uncertainty_score":0.6297884,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.010348071658754,"score_gpt":0.2551742982450175,"score_spread":0.2448262265862635,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}