{"id":"W2006920438","doi":"10.1007/s00253-014-5784-6","title":"Candidacidal mechanism of the arenicin-3-derived peptide NZ17074 from Arenicola marina","year":2014,"lang":"en","type":"article","venue":"Applied Microbiology and Biotechnology","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Chinese Academy of Sciences; Institute of Genetics; National Natural Science Foundation of China","keywords":"Propidium iodide; Candida albicans; DAPI; Biology; Biochemistry; Cell biology; Apoptosis; Fragmentation (computing); Arenicola; Molecular biology; Chemistry; Programmed cell death; Microbiology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0001918619,0.000360912,0.0006713645,0.0001335046,0.0003421895,0.00001001053,0.0005903277,0.00135946,0.0002933347],"category_scores_gemma":[0.00004873468,0.0002580031,0.0001426363,0.0001625373,0.002033487,0.00003341899,0.0006588744,0.0007237038,0.00009971753],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002549849,"about_ca_system_score_gemma":0.0000465285,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004718753,"about_ca_topic_score_gemma":0.0003870601,"domain_scores_codex":[0.9982274,0.0001521665,0.0004422437,0.0006107679,0.00001811216,0.0005492692],"domain_scores_gemma":[0.9987708,0.0002241753,0.0003356577,0.0006116653,0.00003569968,0.00002202786],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001447111,0.00006168929,0.0003798751,0.00001347453,0.0001795832,7.334445e-7,0.0001082434,6.962122e-7,0.9257079,0.06844496,0.001049162,0.003909012],"study_design_scores_gemma":[0.001285867,0.0001585736,0.001153884,0.00002905545,0.00009372716,0.0001238514,0.0002932654,0.000002047183,0.9704156,0.006502016,0.01964556,0.0002965406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947923,0.0004767721,0.0008897206,0.001394832,0.0006072736,0.0003565203,0.0002105924,0.0001358983,0.001136115],"genre_scores_gemma":[0.9979675,0.0001341821,0.0004305243,0.0007674688,0.00004065151,0.00001992336,0.0001394341,0.00002505401,0.0004752726],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06194294,"threshold_uncertainty_score":0.9999872,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004615611590131165,"score_gpt":0.1717221233595423,"score_spread":0.1671065117694111,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}