{"id":"W2006920438","doi":"10.1007/s00253-014-5784-6","title":"Candidacidal mechanism of the arenicin-3-derived peptide NZ17074 from Arenicola marina","year":2014,"lang":"en","type":"article","venue":"Applied Microbiology and Biotechnology","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Chinese Academy of Sciences; Institute of Genetics; National Natural Science Foundation of China","keywords":"Propidium iodide; Candida albicans; DAPI; Biology; Biochemistry; Cell biology; Apoptosis; Fragmentation (computing); Arenicola; Molecular biology; Chemistry; Programmed cell death; Microbiology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001011699,0.000371191,0.0002433528,0.0001716336,0.0001888623,0.0002656038,0.0002788566,0.0002763033,0.0009750809],"category_scores_gemma":[0.00008456328,0.00007355381,0.0002818615,0.00009761371,0.0001959792,0.0001562067,0.0002109275,0.0004800221,0.0002182756],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001597636,"about_ca_system_score_gemma":0.0002101731,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009051252,"about_ca_topic_score_gemma":0.000627667,"domain_scores_codex":[0.9999449,0.000009307482,0.000002833299,0.000008066801,0.00001520264,0.00001953424],"domain_scores_gemma":[0.9999437,0.000008609613,0.00001044742,0.00000455078,0.00001740373,0.00001526623],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000169388,0.00002302469,0.00008074027,0.00003185177,0.00000290774,0.00004388228,0.000008753208,0.00003570248,0.9987633,0.00004711734,0.0000128041,0.0007805345],"study_design_scores_gemma":[0.0000535286,0.0006591434,0.00620688,0.00001057129,0.0000243561,0.0001982058,0.0000593349,0.0006333095,0.9904862,0.00008050874,0.001579654,0.000008369497],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969313,0.0009798502,0.0005991301,0.0000465617,0.00002406745,0.00002693706,0.00007712588,0.0000121971,0.001302724],"genre_scores_gemma":[0.9971142,0.0004027516,0.0005066656,0.00004473238,0.00001110018,0.0000155535,0.000239776,0.000004367439,0.001660881],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009750809,"threshold_uncertainty_score":0.003261924,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004615611590131165,"score_gpt":0.1717221233595423,"score_spread":0.1671065117694111,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}