{"id":"W2006981794","doi":"10.1016/j.bbamem.2005.06.013","title":"Preparation and in vivo evaluation of PEGylated spherulite formulations","year":2005,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Biomembranes","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"Canada Research Chairs","keywords":"Vesicle; Spherulite (polymer physics); In vivo; PEG ratio; Liposome; Materials science; Ethylene glycol; Lamellar structure; Aqueous solution; Chemistry; Pharmacokinetics; Chromatography; Biophysics; Membrane; Organic chemistry; Nanotechnology; Crystallography; Biochemistry; Nucleation; Pharmacology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005192512,0.0005368656,0.0004376059,0.0002909775,0.0002255612,0.0003105841,0.0002007594,0.0006062323,0.001009818],"category_scores_gemma":[0.0002879408,0.0002071992,0.0003601889,0.0002453885,0.0003849847,0.0004986785,0.0001303452,0.0009468389,0.0002744406],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003941395,"about_ca_system_score_gemma":0.0003557673,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008629782,"about_ca_topic_score_gemma":0.000943204,"domain_scores_codex":[0.9997703,0.00004142705,0.0000206755,0.00005357522,0.00005421161,0.00005977323],"domain_scores_gemma":[0.9997428,0.00006668352,0.00007288496,0.0000347438,0.00004061792,0.0000421414],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000624638,0.0002388641,0.00005012138,0.00003379514,0.00001003927,0.00003188832,0.00002847402,0.0001939932,0.9975255,0.00007450649,0.00005515139,0.001132997],"study_design_scores_gemma":[0.00003127595,0.0008040175,0.0003247419,0.000001463719,0.00001402606,0.00003437674,0.000007443793,0.0005957153,0.9977065,0.00001388881,0.0004640881,0.00000240195],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9845521,0.001197519,0.01134784,0.0002058784,0.0001448471,0.0002871141,0.0009059721,0.0001993979,0.001159522],"genre_scores_gemma":[0.9854925,0.001167331,0.007829355,0.00009399222,0.0000364433,0.0002180056,0.0009286219,0.0000925313,0.004141162],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001009818,"threshold_uncertainty_score":0.003378212,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01564261250880648,"score_gpt":0.3057561623159815,"score_spread":0.290113549807175,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}