{"id":"W2007041007","doi":"10.1016/j.vaccine.2009.07.060","title":"Superior efficacy of a recombinant flagellin:H5N1 HA globular head vaccine is determined by the placement of the globular head within flagellin","year":2009,"lang":"en","type":"article","venue":"Vaccine","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":92,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Flagellin; Immunogenicity; Hemagglutinin (influenza); Virology; Influenza A virus subtype H5N1; Biology; Microbiology; Antigen; Immunology; Virus; Receptor; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000780713,0.0002542909,0.0003395692,0.0002403377,0.0001598464,0.0002652591,0.0002745486,0.0004780334,0.002154757],"category_scores_gemma":[0.0006228699,0.0001502473,0.0001841015,0.000134424,0.0004974761,0.000446941,0.0001822288,0.0006279698,0.0003802965],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003277949,"about_ca_system_score_gemma":0.0003695104,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006853359,"about_ca_topic_score_gemma":0.0005857763,"domain_scores_codex":[0.999738,0.00008441445,0.00001798424,0.00004183867,0.0000473453,0.0000704182],"domain_scores_gemma":[0.9996501,0.0001335915,0.00005514466,0.00003507211,0.00005089422,0.00007512888],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005493259,0.0005792763,0.0008375061,0.0000777012,0.00001847057,0.00003163311,0.00004598914,0.0003134621,0.9866367,0.0002445911,0.00014694,0.005574476],"study_design_scores_gemma":[0.0007481661,0.02354389,0.008840867,0.00001422192,0.00006325777,0.0002365469,0.00005482377,0.001399333,0.9632019,0.0002358831,0.00165094,0.00001010643],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982114,0.0005003249,0.000453841,0.00009502678,0.00002696946,0.00001910684,0.00007512292,0.00001117934,0.0006070373],"genre_scores_gemma":[0.9985618,0.0001726268,0.0004574557,0.00004935527,0.00002103811,0.000007616318,0.0001479356,0.000005881041,0.0005762284],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002154757,"threshold_uncertainty_score":0.007208407,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03865246875593456,"score_gpt":0.3393285477556849,"score_spread":0.3006760789997504,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}