{"id":"W2007072747","doi":"10.1093/molbev/mss207","title":"The Timing of Pigmentation Lightening in Europeans","year":2012,"lang":"en","type":"article","venue":"Molecular Biology and Evolution","topic":"melanin and skin pigmentation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":170,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Human Genome Research Institute; Fundação para a Ciência e a Tecnologia; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Government of Ontario; Ontario Innovation Trust","keywords":"Biology; Selective sweep; Haplotype; Evolutionary biology; Genetics; Balancing selection; Single-nucleotide polymorphism; Allele; Gene; Genotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004846994,0.00008547927,0.0001822104,0.0005628344,0.0001510542,0.0004249794,0.0001331654,0.0002842864,0.0008855863],"category_scores_gemma":[0.001397943,0.0001394349,0.0001838014,0.0003326046,0.000314509,0.0001839757,0.0002888908,0.0001821013,0.0001818098],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000173391,"about_ca_system_score_gemma":0.00009962945,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001955669,"about_ca_topic_score_gemma":0.002560168,"domain_scores_codex":[0.9998105,0.00005717789,0.000009060826,0.00007996888,0.0000184507,0.00002488281],"domain_scores_gemma":[0.9994703,0.0001849746,0.0001747739,0.00004046266,0.000057533,0.0000719334],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007592404,0.00003796202,0.8860745,0.00004235527,0.0001257032,0.000303822,0.000875254,0.003416893,0.08398409,0.0008057583,0.0001254234,0.02344906],"study_design_scores_gemma":[0.000007059847,0.00005058436,0.995349,0.000006755152,0.00001428239,0.0002699813,0.00011522,0.001598899,0.001909193,0.0002426545,0.0004277881,0.000008668411],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991797,0.0001295329,0.0003599594,0.000009000852,0.000001092644,9.241392e-7,0.00003533874,0.000006465967,0.0002780052],"genre_scores_gemma":[0.9995418,0.0000494112,0.0002118481,0.000006095045,0.000001384733,0.000001076545,0.00007290366,0.000003451285,0.0001119775],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001955669,"threshold_uncertainty_score":0.003888607,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00861435994075866,"score_gpt":0.2797478550502596,"score_spread":0.271133495109501,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}