{"id":"W2007103582","doi":"10.1016/j.febslet.2014.02.041","title":"RASSF tumor suppressor gene family: Biological functions and regulation","year":2014,"lang":"en","type":"review","venue":"FEBS Letters","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":136,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Biology; Cancer research; Tumor suppressor gene; Epigenetics; Gene silencing; Suppressor; DNA methylation; Cancer; Gene; Genetics; Gene expression; Carcinogenesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002350862,0.0003101031,0.0005608525,0.00008220666,0.0001044544,0.0000461093,0.0001420454,0.0003243203,0.00001396464],"category_scores_gemma":[0.00007243891,0.000253305,0.0002322748,0.00008248159,0.00009468634,0.000002412386,0.0001131554,0.0001504703,0.00003144464],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001656639,"about_ca_system_score_gemma":0.00003970354,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005921032,"about_ca_topic_score_gemma":0.000002117565,"domain_scores_codex":[0.9985092,0.0002229154,0.0003651521,0.000560983,0.0001066101,0.0002351697],"domain_scores_gemma":[0.9992043,0.00004212485,0.0002254924,0.0004069137,0.00003446211,0.00008668097],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003083892,0.00005909858,0.0001588462,0.002045129,0.0003222115,0.000007938766,0.00001055533,0.00004712889,0.4857428,0.00005816431,0.01300439,0.4985129],"study_design_scores_gemma":[0.000145008,0.0000919651,0.000259401,0.0001929578,0.0001504819,0.000009335296,0.000001634489,0.000007565592,0.001644509,0.00001339135,0.9971732,0.0003105279],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01315958,0.9811491,0.004526402,0.00009433389,0.0003629879,0.0003996904,0.00007114969,0.00002064331,0.0002160739],"genre_scores_gemma":[0.001248838,0.9943055,0.0006241805,0.0004160509,0.0009099554,0.00008640558,0.002047369,0.0000488869,0.0003128351],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9841688,"threshold_uncertainty_score":0.9999919,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03265687682270404,"score_gpt":0.2848628494387107,"score_spread":0.2522059726160066,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}