{"id":"W2007121264","doi":"10.1089/nat.2011.0286","title":"Structural Diversity Repertoire of Gene Silencing Small Interfering RNAs","year":2011,"lang":"en","type":"review","venue":"Nucleic Acid Therapeutics","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"PCL Construction (Canada)","funders":"","keywords":"RNA interference; Gene silencing; Trans-acting siRNA; Small interfering RNA; RNA silencing; Biology; RNA-induced silencing complex; Cell biology; Gene; Computational biology; Genetics; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003033107,0.0007338511,0.0009517468,0.001344047,0.0002207511,0.0007230482,0.0007517604,0.000667469,0.00140993],"category_scores_gemma":[0.0002441762,0.0003930659,0.0003099703,0.001105972,0.0003409916,0.0008396735,0.0003913433,0.0008985153,0.00187655],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005232737,"about_ca_system_score_gemma":0.0004933226,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004290236,"about_ca_topic_score_gemma":0.0005572333,"domain_scores_codex":[0.9998671,0.00001397065,0.00001634325,0.00003658071,0.0000524618,0.00001361834],"domain_scores_gemma":[0.9999201,0.00002886847,0.00001355171,0.000004326128,0.00002416956,0.00000889463],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009810872,0.00007406094,0.000270199,0.01128351,0.00006748935,0.0005505845,0.0001083552,0.001160899,0.1051387,0.0111067,0.004276091,0.8658652],"study_design_scores_gemma":[0.00002315228,0.0002620541,0.00103785,0.0008610038,0.00009239151,0.003298798,0.00004652791,0.0004051823,0.04255956,0.003283191,0.9480921,0.00003820531],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002580603,0.9863072,0.00306742,0.0002039281,0.0001294138,0.00002541217,0.00007322108,0.00005637769,0.007556396],"genre_scores_gemma":[0.00901902,0.984278,0.003212312,0.0001885062,0.00009268594,0.00004820007,0.0001602233,0.00001076595,0.002990242],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00140993,"threshold_uncertainty_score":0.004716635,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0918651809273033,"score_gpt":0.2898918200729756,"score_spread":0.1980266391456723,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}