{"id":"W2007123568","doi":"10.1016/j.devcel.2011.03.011","title":"Hox and Pbx Factors Control Retinoic Acid Synthesis during Hindbrain Segmentation","year":2011,"lang":"en","type":"article","venue":"Developmental Cell","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Dental and Craniofacial Research; Agence Nationale pour le Développement de la Recherche en Santé; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Agence Nationale de la Recherche; Fondation pour la recherche juridique; National Institutes of Health; Fondation pour l'Aide à la Recherche sur la Sclérose en Plaques; March of Dimes Foundation","keywords":"Hox gene; Hindbrain; Rhombomere; Retinoic acid; Biology; Mesoderm; Cell biology; Phenotype; Lateral plate mesoderm; Genetics; Embryo; Gene expression; Embryonic stem cell; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001005489,0.0001797479,0.0001241296,0.00003792423,0.0001284682,0.00002212081,0.0001244893,0.0001227197,0.0001164942],"category_scores_gemma":[0.00003795914,0.0001674728,0.00003965446,0.00004889105,0.00007563415,0.000008794376,0.00007402241,0.00006769563,0.00001690045],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003405134,"about_ca_system_score_gemma":0.00005962932,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000110257,"about_ca_topic_score_gemma":0.000003084183,"domain_scores_codex":[0.9991118,0.00004374021,0.0001864793,0.0003255582,0.0001105328,0.0002218895],"domain_scores_gemma":[0.9996932,0.00001086422,0.00007811487,0.0001076036,0.00002647655,0.00008374169],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000623099,0.00003148469,0.0485535,0.00006097254,0.00002879438,0.000006399991,0.0005530431,2.749936e-7,0.9499729,0.000003501547,0.00007013768,0.0006566955],"study_design_scores_gemma":[0.0005036795,0.00004854905,0.03036282,0.00001111642,0.00001683427,0.00001734968,0.0008282695,0.000001776951,0.9674813,0.00001472973,0.0004867559,0.0002268532],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992462,0.0004626629,0.0003664786,0.000006713449,0.00007422963,0.0001465216,0.00001123974,0.00001795036,0.006452157],"genre_scores_gemma":[0.9962177,0.0001621486,0.002644423,0.00007033123,0.00003811431,0.00003303502,0.00005563242,0.00002437127,0.0007542055],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01819068,"threshold_uncertainty_score":0.682934,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009159834295660682,"score_gpt":0.1828856172834979,"score_spread":0.1737257829878373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}