{"id":"W2007153997","doi":"10.1053/j.gastro.2011.10.038","title":"The Copolymer P(HEMA-co-SS) Binds Gluten and Reduces Immune Response in Gluten-Sensitized Mice and Human Tissues","year":2011,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Celiac Disease Research and Management","field":"Medicine","cited_by":80,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; Population Health Research Institute; Université de Sherbrooke; Université de Montréal","funders":"Canadian Institutes of Health Research; Grantová Agentura České Republiky; Canadian Association of Gastroenterology; Fonds Québécois de la Recherche sur la Nature et les Technologies; Canadian Celiac Association; Natural Sciences and Engineering Research Council of Canada; McMaster University","keywords":"Gliadin; Hordein; Chemistry; Gluten; Intestinal permeability; Immune system; Bioavailability; Pharmacology; Biochemistry; Immunology; Medicine; Storage protein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001866197,0.0003232564,0.0001970781,0.0003084127,0.0001585784,0.0001765503,0.0001509027,0.0004474067,0.002718564],"category_scores_gemma":[0.0001443516,0.0002236747,0.0001914008,0.0001262636,0.0002125381,0.0003730165,0.0001728785,0.0006063522,0.0006264049],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001290471,"about_ca_system_score_gemma":0.0001737014,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004077328,"about_ca_topic_score_gemma":0.0004692446,"domain_scores_codex":[0.9998511,0.0000318771,0.000007098959,0.00003409496,0.00002596181,0.00004972999],"domain_scores_gemma":[0.9998295,0.00004766397,0.00004130834,0.00001868318,0.00001187548,0.00005080083],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002774398,0.00007402314,0.0001330417,0.00002294622,0.000005392362,0.0000307243,0.000004759873,0.00005608685,0.9982244,0.00003703189,0.00003367843,0.001100478],"study_design_scores_gemma":[0.00002403356,0.00131746,0.003294059,0.000004392803,0.0000175564,0.0001875103,0.00001041757,0.0005527996,0.9938114,0.00002937,0.0007478452,0.000003143892],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936893,0.001303785,0.002304374,0.0001299801,0.0000552562,0.00002467518,0.00008788564,0.00009615783,0.002308554],"genre_scores_gemma":[0.9941109,0.0005707881,0.001349264,0.00008651624,0.00003191122,0.00002233193,0.0001887061,0.00003328558,0.003606308],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002718564,"threshold_uncertainty_score":0.009094536,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01976412034344453,"score_gpt":0.2972239922871119,"score_spread":0.2774598719436673,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}