{"id":"W2007256551","doi":"10.1016/j.biomaterials.2011.03.061","title":"Decoration of polymeric micelles with cancer-specific peptide ligands for active targeting of paclitaxel","year":2011,"lang":"en","type":"article","venue":"Biomaterials","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":80,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Micelle; Paclitaxel; Cytotoxicity; Peptide; Cancer cell; Ethylene oxide; Chemistry; In vitro; Cell culture; Biochemistry; Biophysics; Copolymer; Cancer; Biology; Organic chemistry; Aqueous solution","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003765224,0.0001532779,0.0003612336,0.00008548787,0.00006052438,0.00002163411,0.0001782952,0.00005777925,0.0004775027],"category_scores_gemma":[0.0000507979,0.0001219787,0.00005127596,0.0001572526,0.000166063,0.0002302552,0.00003685422,0.000005322833,0.00001361914],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003387593,"about_ca_system_score_gemma":0.0001013267,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006365518,"about_ca_topic_score_gemma":0.00002308809,"domain_scores_codex":[0.9987369,0.00004683059,0.0005212099,0.0002682927,0.0001725767,0.0002541501],"domain_scores_gemma":[0.9987919,0.0001151238,0.0005884538,0.0002227493,0.0002274674,0.00005433398],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001330229,0.0001125036,0.000561211,0.0001100855,0.00001805826,0.000001139415,0.001062615,0.000003360379,0.9962167,0.0001276471,0.0002478059,0.0002086409],"study_design_scores_gemma":[0.0006397539,0.0003561675,0.001464926,0.00008927335,0.0000358807,0.000001153909,0.0005912292,0.000007018535,0.9965236,0.00008092444,0.00005939257,0.0001506742],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979269,0.000371795,0.0002749203,0.00002674997,0.0004621062,0.0004179491,0.0004392919,0.00004301818,0.00003725722],"genre_scores_gemma":[0.9936988,0.0000380094,0.005999693,0.00001077692,0.00009254956,0.0001010691,0.00001862665,0.00002521785,0.00001521941],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005724773,"threshold_uncertainty_score":0.522832,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03147974934124611,"score_gpt":0.251526382746228,"score_spread":0.2200466334049819,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}