{"id":"W2007318061","doi":"10.1002/ajmg.a.33251","title":"Review and hypothesis: Syndromes with severe intrauterine growth restriction and very short stature—Are they related to the epigenetic mechanism(s) of fetal survival involved in the developmental origins of adult health and disease?","year":2010,"lang":"en","type":"review","venue":"American Journal of Medical Genetics Part A","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's & Women's Health Centre of British Columbia","funders":"","keywords":"Epigenetics; Intrauterine growth restriction; Fetus; DNA methylation; Mechanism (biology); Biology; Disease; Epigenesis; Short stature; Genomic imprinting; Genetics; Phenotype; Natural history; Bioinformatics; Physiology; Pregnancy; Medicine; Endocrinology; Gene; Internal medicine; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001040082,0.0002936598,0.001171993,0.00009923231,0.00005348412,0.00001777933,0.0003935296,0.0001339761,0.000003158558],"category_scores_gemma":[0.0005341069,0.0001600869,0.0001046716,0.0002752529,0.0003144708,0.000003671689,0.0001880093,0.0004640405,1.445165e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000227358,"about_ca_system_score_gemma":0.0008868849,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004286435,"about_ca_topic_score_gemma":0.0001095061,"domain_scores_codex":[0.9974933,0.0004708438,0.0009569332,0.0002965938,0.0005369288,0.0002453754],"domain_scores_gemma":[0.998272,0.0001278979,0.0007978175,0.0002441288,0.0001371845,0.0004209834],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005576036,0.0001399378,0.004258398,0.008572762,0.0005741424,0.00003038926,0.0004041707,0.000001586141,0.00003492219,0.0001307221,0.0001760784,0.9856212],"study_design_scores_gemma":[0.004531893,0.02323804,0.0790974,0.1599532,0.007336994,0.01985561,0.0112989,0.00005012838,0.0001416924,0.001087759,0.6899896,0.003418828],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.2306757,0.7677379,0.00005759756,0.0009301257,0.00008092218,0.0004791305,0.00003416872,0.000001181646,0.000003303052],"genre_scores_gemma":[0.07870991,0.9197505,0.001045347,0.0003924445,0.00004270753,0.00001698028,0.00001432513,0.00002652204,0.000001322251],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9822023,"threshold_uncertainty_score":0.6528154,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0204076349924515,"score_gpt":0.2853311782416312,"score_spread":0.2649235432491797,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}