{"id":"W2007318061","doi":"10.1002/ajmg.a.33251","title":"Review and hypothesis: Syndromes with severe intrauterine growth restriction and very short stature—Are they related to the epigenetic mechanism(s) of fetal survival involved in the developmental origins of adult health and disease?","year":2010,"lang":"en","type":"review","venue":"American Journal of Medical Genetics Part A","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's & Women's Health Centre of British Columbia","funders":"","keywords":"Epigenetics; Intrauterine growth restriction; Fetus; DNA methylation; Mechanism (biology); Biology; Disease; Epigenesis; Short stature; Genomic imprinting; Genetics; Phenotype; Natural history; Bioinformatics; Physiology; Pregnancy; Medicine; Endocrinology; Gene; Internal medicine; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004841411,0.001312925,0.00183709,0.002484162,0.0003633538,0.00112964,0.001590574,0.001678536,0.007196526],"category_scores_gemma":[0.001353582,0.0002812505,0.0003935728,0.003330299,0.001070769,0.002972649,0.0007957197,0.002257891,0.005475822],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007363562,"about_ca_system_score_gemma":0.001244264,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009293722,"about_ca_topic_score_gemma":0.001593952,"domain_scores_codex":[0.9998149,0.0000387727,0.00003152051,0.00003670135,0.00006344369,0.00001477327],"domain_scores_gemma":[0.9995186,0.0002143777,0.00007846276,0.00001300245,0.0001011722,0.0000742728],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0001048655,0.00006119871,0.0003281512,0.01594328,0.00009396801,0.0008063079,0.00008918384,0.0003000095,0.0008895902,0.004209993,0.3079937,0.6691797],"study_design_scores_gemma":[0.00002693196,0.00004181377,0.001019225,0.003177326,0.00006525661,0.004667734,0.00008836287,0.00004846958,0.00009347239,0.002198879,0.9885553,0.00001728678],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009664246,0.9939826,0.00015319,0.001353764,0.00237662,0.00001082618,0.00003690461,0.00001548338,0.001973958],"genre_scores_gemma":[0.0006029664,0.9947098,0.0002590698,0.001271167,0.001756455,0.00001693959,0.00006325654,0.000003288757,0.001316977],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.007196526,"threshold_uncertainty_score":0.02407473,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0204076349924515,"score_gpt":0.2853311782416312,"score_spread":0.2649235432491797,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}