{"id":"W2007349210","doi":"10.1172/jci32214","title":"Murine models of Omenn syndrome","year":2007,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"School of Medicine, New York University; York University","keywords":"Immunology; Severe combined immunodeficiency; Immunodeficiency; Autoimmunity; Disease; Wiskott–Aldrich syndrome; RAG2; Immunodeficiency Syndrome; Immune dysregulation; Medicine; Pathogenesis; Biology; Immune system; Genetics; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004382583,0.0003022069,0.0030217,0.0004146324,0.00006427059,0.000009180994,0.0005692239,0.001049564,0.0001483719],"category_scores_gemma":[0.000910493,0.0002215387,0.001408364,0.0003676011,0.0006917691,0.0002313025,0.00007514449,0.001632957,0.0001077614],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003400081,"about_ca_system_score_gemma":0.0007039607,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000991154,"about_ca_topic_score_gemma":3.098368e-7,"domain_scores_codex":[0.993512,0.0007468903,0.005139447,0.000211733,0.0001236176,0.0002662586],"domain_scores_gemma":[0.992768,0.001222625,0.005339183,0.0003281386,0.0003170294,0.00002500903],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005000312,0.0002920379,0.00001329174,0.002783941,0.0007605681,0.00002329963,0.00008534912,0.00002633985,0.00003613476,0.001110659,0.000326453,0.9944919],"study_design_scores_gemma":[0.001019693,0.000701324,0.00012476,0.01114906,0.001078227,0.0008031225,0.00004350034,0.000004993213,0.00003452275,0.003293592,0.9814782,0.0002689731],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002250049,0.9943749,0.0002595831,0.00003231391,0.002292969,0.000222072,0.00001341774,0.00001116848,0.0005434815],"genre_scores_gemma":[0.004391121,0.9946399,0.0001761156,0.00007055602,0.00002703348,0.000002551323,0.0000769962,0.00002846135,0.0005872915],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9942229,"threshold_uncertainty_score":0.9034085,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1894206740190849,"score_gpt":0.4208101440588122,"score_spread":0.2313894700397273,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}