{"id":"W2007431287","doi":"10.1158/1078-0432.ccr-05-2719","title":"Bcl-2 Is a Prognostic Marker in Breast Cancer Independently of the Nottingham Prognostic Index","year":2006,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":238,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Vancouver General Hospital; University of British Columbia; BC Cancer Agency","funders":"","keywords":"Hazard ratio; Nottingham Prognostic Index; Breast cancer; Oncology; Medicine; Internal medicine; Tissue microarray; Immunohistochemistry; Estrogen receptor; Confidence interval; Cytokeratin; Univariate analysis; Multivariate analysis; Proportional hazards model; Progesterone receptor; Cancer; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001018345,0.0002931816,0.000333757,0.0004619336,0.0002278034,0.0003768739,0.0002596106,0.0002553655,0.001217545],"category_scores_gemma":[0.003104424,0.0001203725,0.0002112872,0.0004781741,0.0003501838,0.0003371074,0.00025459,0.0003934394,0.0002392327],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004000837,"about_ca_system_score_gemma":0.0002891079,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009107413,"about_ca_topic_score_gemma":0.001544274,"domain_scores_codex":[0.9996514,0.0001073574,0.00002604602,0.00006987095,0.0001014583,0.00004384781],"domain_scores_gemma":[0.998365,0.0005338857,0.0005848977,0.0001369624,0.0001439187,0.0002353022],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001659845,0.00005182549,0.9746453,0.00005574303,0.00009617874,0.0002781252,0.00003718329,0.0002835428,0.005732198,0.00005198246,0.0002824627,0.0168257],"study_design_scores_gemma":[0.00005847407,0.0006000463,0.987644,0.00002432673,0.0002189893,0.002051824,0.00004750114,0.002878691,0.005212913,0.0002105985,0.001041717,0.00001091832],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963678,0.001957275,0.0005968154,0.0001627189,0.00003879784,0.00001325344,0.0001193974,0.00001934753,0.0007245031],"genre_scores_gemma":[0.9991441,0.0002222559,0.0002813892,0.00002045834,0.00003073607,0.000008387097,0.0001251794,0.000002262473,0.000165304],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001217545,"threshold_uncertainty_score":0.005385578,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0568880509171121,"score_gpt":0.4291412701146157,"score_spread":0.3722532191975036,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}