{"id":"W2007465432","doi":"10.3899/jrheum.130310","title":"Deregulated NLRP3 and NLRP1 Inflammasomes and Their Correlations with Disease Activity in Systemic Lupus Erythematosus","year":2013,"lang":"en","type":"article","venue":"The Journal of Rheumatology","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Natural Science Foundation of China","keywords":"Inflammasome; Pyrin domain; NLRP1; Medicine; Pathogenesis; Peripheral blood mononuclear cell; Immunology; Apoptosis; Biology; Programmed cell death; Genetics; Caspase; Inflammation","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001954623,0.0001296341,0.0002284135,0.00007271647,0.0000764487,0.00001715174,0.0001118288,0.00008150355,0.000007234687],"category_scores_gemma":[0.00005654446,0.00007364375,0.00003081221,0.00006486959,0.0001991018,0.00001938094,0.00006055081,0.000142881,0.000001841062],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000674071,"about_ca_system_score_gemma":0.00007094748,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006043368,"about_ca_topic_score_gemma":0.0000867084,"domain_scores_codex":[0.9992841,0.0001559025,0.0002466998,0.00009498581,0.00005245621,0.0001657815],"domain_scores_gemma":[0.9993717,0.00007173666,0.0002346095,0.0001690091,0.00008852876,0.00006442702],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008927584,0.00005268614,0.9428013,0.0001005654,0.0001505248,0.000004954976,0.001134148,0.0002549508,0.05209316,0.000161355,0.0002530845,0.002100529],"study_design_scores_gemma":[0.01453911,0.002274364,0.8626134,0.001182973,0.0003145994,0.07687744,0.0141081,0.003221637,0.01858635,0.003937803,0.00109043,0.001253836],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946014,0.004200931,0.0003664802,0.000546402,0.00007194874,0.0001764643,0.00000144769,0.00000311953,0.00003183725],"genre_scores_gemma":[0.9978738,0.001992152,0.0000244176,0.00002684708,0.000004005003,0.000006369068,0.000002653579,0.00001179521,0.00005789073],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08018792,"threshold_uncertainty_score":0.3003105,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003780516281911246,"score_gpt":0.1888337093334994,"score_spread":0.1850531930515882,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}