{"id":"W2007465432","doi":"10.3899/jrheum.130310","title":"Deregulated NLRP3 and NLRP1 Inflammasomes and Their Correlations with Disease Activity in Systemic Lupus Erythematosus","year":2013,"lang":"en","type":"article","venue":"The Journal of Rheumatology","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Natural Science Foundation of China","keywords":"Inflammasome; Pyrin domain; NLRP1; Medicine; Pathogenesis; Peripheral blood mononuclear cell; Immunology; Apoptosis; Biology; Programmed cell death; Genetics; Caspase; Inflammation","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004300333,0.0003273227,0.0003589689,0.0005360863,0.000192807,0.0003699443,0.0001207506,0.0003341244,0.001070003],"category_scores_gemma":[0.0006834622,0.0001207392,0.0002628737,0.0005866194,0.00023555,0.0002399544,0.000167714,0.0004693598,0.0002295102],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001110783,"about_ca_system_score_gemma":0.0001081895,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000138243,"about_ca_topic_score_gemma":0.000172098,"domain_scores_codex":[0.9997318,0.0000674687,0.00006139943,0.00005309453,0.00006114997,0.00002505407],"domain_scores_gemma":[0.999158,0.0001141912,0.0005135306,0.00002660991,0.00008080692,0.0001069609],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004056395,0.0003230867,0.8029189,0.0005964923,0.0003850821,0.002331155,0.0004371009,0.0002888828,0.1685351,0.00009167688,0.0002942239,0.01974182],"study_design_scores_gemma":[0.00007456556,0.0006695085,0.9854151,0.00003420697,0.0001712846,0.005397548,0.0001566926,0.000454067,0.006605421,0.0001308797,0.0008777171,0.00001304148],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928798,0.006205809,0.0004030631,0.00005922369,0.00001301562,0.00001099195,0.0001426651,0.00001952362,0.0002658523],"genre_scores_gemma":[0.998372,0.0008241711,0.0003819492,0.00002921632,0.00003485476,0.00001221271,0.0001469382,0.000002071308,0.0001966373],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001070003,"threshold_uncertainty_score":0.003579497,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003780516281911246,"score_gpt":0.1888337093334994,"score_spread":0.1850531930515882,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}