{"id":"W2007471444","doi":"10.1016/j.brainres.2005.10.009","title":"The Survivin-mediated radioresistant phenotype of glioblastomas is regulated by RhoA and inhibited by the green tea polyphenol (−)-epigallocatechin-3-gallate","year":2006,"lang":"en","type":"article","venue":"Brain Research","topic":"Tea Polyphenols and Effects","field":"Medicine","cited_by":66,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Université du Québec à Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Survivin; RHOA; Radioresistance; Transfection; Cancer research; Apoptosis; Cell growth; Chemistry; Cancer cell; Epigallocatechin gallate; Biology; Molecular biology; Signal transduction; Cell biology; Cell culture; Cancer; Biochemistry; Polyphenol; Antioxidant","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003488597,0.0003147914,0.0004710233,0.0002078318,0.000646255,0.0001136422,0.0004662741,0.0002514109,0.00008941142],"category_scores_gemma":[0.0008352019,0.000179647,0.0001042825,0.001426985,0.001277847,0.00007256361,0.0002560907,0.0008538764,0.00004490644],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001114771,"about_ca_system_score_gemma":0.0002087341,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01319413,"about_ca_topic_score_gemma":0.001028868,"domain_scores_codex":[0.9955822,0.0008149944,0.0005848348,0.0005424074,0.001444257,0.001031308],"domain_scores_gemma":[0.9957245,0.002544956,0.0001571122,0.0009228984,0.0003891242,0.0002614192],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00114338,0.0002052591,0.002667534,0.0001421628,0.0001637343,0.00002168699,0.000553837,9.872758e-7,0.5884134,0.0005011006,0.3949077,0.01127926],"study_design_scores_gemma":[0.01402518,0.004230627,0.2080606,0.0009178156,0.0002370205,0.0001767548,0.001428956,0.006150707,0.2901748,0.003033424,0.4702268,0.001337292],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.948105,0.008934616,0.00001761172,0.03959227,0.00005537357,0.001082591,0.0001429383,0.0001086803,0.001960955],"genre_scores_gemma":[0.9774255,0.0001987983,0.00002423797,0.0003869238,0.0001268906,0.00004840399,0.00009584564,0.00008140942,0.02161201],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2982386,"threshold_uncertainty_score":0.9933771,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01405037922781031,"score_gpt":0.2905457088252756,"score_spread":0.2764953295974653,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}